RAPTOR 抗体 (pSer792) (Biotin)
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- 抗原 See all RAPTOR 抗体
- RAPTOR
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抗原表位
- pSer792
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适用
- 人, 小鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RAPTOR antibody is conjugated to Biotin
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应用范围
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 斑马鱼
- 预测反应
- Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from mouse Raptor around the phosphorylation site of Ser792
- 亚型
- IgG
- Top Product
- Discover our top product RAPTOR Primary Antibody
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anti-RAPTOR (RAPTOR) (pSer863) antibody
RAPTOR 适用: 人 WB, DB, IHC (p) 宿主: 兔 Polyclonal RB24817-24818 unconjugated
anti-RAPTOR (RAPTOR) antibodyRAPTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 1411CT316-2-151-34 unconjugated
anti-RAPTOR (RAPTOR) (AA 101-200) antibodyRAPTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-RAPTOR (RAPTOR) (pSer863) antibodyRAPTOR 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
anti-RAPTOR (RAPTOR) (C-Term) antibodyRAPTOR 适用: 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-RAPTOR (RAPTOR) (N-Term) antibodyRAPTOR 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RAPTOR
- 别名
- Raptor (RAPTOR 产品)
- 别名
- KOG1 antibody, Mip1 antibody, 4932417H02Rik antibody, Rap antibody, Raptor antibody, mKIAA1303 antibody, RGD1311784 antibody, regulatory associated protein of MTOR complex 1 antibody, regulatory associated protein of MTOR, complex 1 antibody, RPTOR antibody, Rptor antibody
- 背景
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Synonyms: ARaptor phospho S792, Raptor phospho Ser792, p-Raptor Ser792, p150 target of rapamycin TOR scaffold protein containing WD repeats, P150 target of rapamycin TOR-scaffold protein, Regulatory Associated Protein of mTOR, KIAA1303, RPTOR_HUMAN, Regulatory-associated protein of mTOR, p150 target of rapamycin TOR-scaffold protein.
Background: mTOR controls cell growth, in part by regulating p70 S6 kinase alpha (p70alpha) and eukaryotic initiation factor 4E binding protein 1 (4EBP1). Raptor is a 150 kDa mTOR binding protein that also binds 4EBP1 and p70alpha. The binding of Raptor to mTOR is necessary for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro, and it strongly enhances the mTOR kinase activity toward p70alpha. Rapamycin or amino acid withdrawal increases, whereas insulin strongly inhibits, the recovery of 4EBP1 and raptor on 7-methyl-GTP Sepharose. Partial inhibition of raptor expression by RNA interference (RNAi) reduces mTOR-catalyzed 4EBP1 phosphorylation in vitro. RNAi of C. elegans raptor yields an array of phenotypes that closely resemble those produced by inactivation of Ce-TOR. Thus, raptor is an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.
- 途径
- Warburg Effect
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