RPS6KA2 抗体 (pSer360, pThr356)
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- 抗原 See all RPS6KA2 抗体
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
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抗原表位
- pSer360, pThr356
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RPS6KA2 antibody is un-conjugated
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应用范围
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic phosphopeptide derived from human RSK3 around the phosphorylation site of Thr356/Ser360
- 亚型
- IgG
- Top Product
- Discover our top product RPS6KA2 Primary Antibody
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- 应用备注
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
- 别名
- RSK3 + (RPS6KA2 产品)
- 别名
- HU-2 antibody, MAPKAPK1C antibody, RSK antibody, RSK3 antibody, S6K-alpha antibody, S6K-alpha2 antibody, p90-RSK3 antibody, pp90RSK3 antibody, 90kDa antibody, D17Wsu134e antibody, Rps6ka-rs1 antibody, Rsk3 antibody, p90rsk antibody, pp90rsk antibody, ribosomal protein S6 kinase A2 antibody, ribosomal protein S6 kinase, polypeptide 2 antibody, Rps6ka2 antibody, RPS6KA2 antibody
- 背景
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Synonyms: 90 kDa ribosomal protein S6 kinase 2, HU 2, KS6A2_HUMAN, MAP kinase activated protein kinase 1c, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, MAPKAPK1C, p90-RSK 2, p90RSK 2, p90RSK2, pp90RSK 3, pp90RSK3, Ribosomal protein S6 kinase alpha-2, Ribosomal S6 kinase 3, RPS6KA2, RSK 3, RSK-3, S6K alpha 2, S6K alpha, S6K-alpha-2.
Background: RSK3(Ribosomal S6 kinase 3)is a member of a family of 90- kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine/threonine protein kinases that are activated in response to mitogenic stimuli, including extracellular signal-regulated protein kinases Erk1 and Erk2. Rsk3 is a distinct isoform of p90Rsk that translocates to the cell nucleus, phosphorylates potential nuclear targets and may have a unique upstream activator. Several sites, such as Ser380, Thr359, Ser363 and Thr573, are important for its activation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c Fos and CREB.
- 基因ID
- 6196
- 途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Activation of Innate immune Response, Toll-Like Receptors Cascades
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