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PEA15 抗体 (pSer104)

PEA15 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN744683
发货至: 中国
  • 抗原 See all PEA15 抗体
    PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))
    抗原表位
    • 15
    • 14
    • 13
    • 12
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer104
    适用
    • 79
    • 46
    • 33
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    宿主
    • 79
    • 2
    克隆类型
    • 81
    多克隆
    标记
    • 43
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PEA15 antibody is un-conjugated
    应用范围
    • 43
    • 41
    • 25
    • 14
    • 14
    • 12
    • 11
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    预测反应
    Human,Mouse,Rat,Dog,Cow,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human PEA15 around the phosphorylation site of Ser104
    亚型
    IgG
    Top Product
    Discover our top product PEA15 Primary Antibody
  • 应用备注
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Kim, Kang: "PKC, AKT and ERK1/2-Mediated Modulations of PARP1, NF-κB and PEA15 Activities Distinctly Regulate Regional Specific Astroglial Responses Following Status Epilepticus." in: Frontiers in molecular neuroscience, Vol. 12, pp. 180, (2019) (PubMed).

  • 抗原
    PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))
    别名
    PEA15 (PEA15 产品)
    别名
    HMAT1 antibody, HUMMAT1H antibody, MAT1 antibody, MAT1H antibody, PEA-15 antibody, PED antibody, Pea15a antibody, PEA15 antibody, DKFZp459O1410 antibody, proliferation and apoptosis adaptor protein 15 antibody, phosphoprotein enriched in astrocytes 15 antibody, proliferation and apoptosis adaptor protein 15 L homeolog antibody, Astrocytic phosphoprotein PEA-15 antibody, PEA15 antibody, Pea15 antibody, pea15.L antibody, pea15 antibody
    背景

    Synonyms: Astrocytic phosphoprotein PEA 15, Astrocytic phosphoprotein PEA15, HMAT 1, HMAT1, Homolog of mouse MAT 1 oncogene, Homolog of mouse MAT1 oncogene, HUMMAT 1H, HUMMAT1H, MAT 1, MAT 1H, MAT1, MAT1H, PEA 15, PEA-15_ PEA15 protein, PED, Phosphoprotein enriched in astrocytes 15, Phosphoprotein enriched in astrocytes 15kD, Phosphoprotein enriched in diabetes.

    Background: PED/PEA 15 (Phosphoprotein Enriched in Diabetes/Phosphoprotein Enriched in Astrocytes 15 kDa) is a widely expressed 15 kDa protein comprised of an N terminal region containing a canonical Death Effector Domain (DED) sequence and a nuclear export signal, and a C terminal region containing two serine phosphorylation sites. PED/PEA 15 has been implicated in the regulation of multiple cellular processes including apoptosis, integrin activation, and insulin sensitive glucose transport in insulin responsive cells. Phosphorylation of both serine 104 (a Protein Kinase C site) and serine 116 (a substrate of CaMKII and Akt) is required for PED/PEA 15 function.

    基因ID
    8682
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