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MSK1 抗体 (pSer360)

RPS6KA5 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN743978
发货至: 中国
  • 抗原 See all MSK1 (RPS6KA5) 抗体
    MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
    抗原表位
    • 33
    • 26
    • 23
    • 22
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
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    • 2
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    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    pSer360
    适用
    • 112
    • 107
    • 49
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    小鼠, 大鼠
    宿主
    • 162
    • 4
    • 2
    • 1
    克隆类型
    • 156
    • 13
    多克隆
    标记
    • 83
    • 9
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    This MSK1 antibody is un-conjugated
    应用范围
    • 133
    • 64
    • 52
    • 51
    • 36
    • 27
    • 25
    • 11
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Dog,Cow,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human MSK1 around the phosphorylation site of Ser360 [TY(p-S)PA]
    亚型
    IgG
    Top Product
    Discover our top product RPS6KA5 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    MSK1 (RPS6KA5) (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 5 (RPS6KA5))
    别名
    MSK1 (RPS6KA5 产品)
    别名
    MSK1 antibody, MSPK1 antibody, RLPK antibody, 3110005L17Rik antibody, 6330404E13Rik antibody, AI854034 antibody, Msk1 antibody, ribosomal protein S6 kinase A5 antibody, ribosomal protein S6 kinase, polypeptide 5 antibody, RPS6KA5 antibody, Rps6ka5 antibody
    背景

    Synonyms: MSK1 phospho S360, MSK1 Ser360, MSK1 S360, p-MSK1 Ser360, Pp-MSK1 S360, MSK1, RPS6KA5, 90 kDa ribosomal protein S6 kinase 5, EC 2.7.11.1, KS6A5_HUMAN, MGC1911, Mitogen and stress activated protein kinase 1, MSPK1, Nuclear Mitogen And Stress Activated Protein Kinase 1, Nuclear mitogen- and stress-activated protein kinase 1, Ribosomal protein S6 kinase 90kD polypeptide 5, Ribosomal protein S6 kinase 90 kDa, Ribosomal protein S6 kinase 90 kDa polypeptide 5, Ribosomal Protein S6 Kinase Alpha 5, Ribosomal protein S6 kinase alpha-5, RLPK, RSK Like Protein Kinase, RSK-like protein kinase, RSKL, S6K alpha 5, S6K-alpha-5.

    Background: MSK1 is a mitogen and stress activated protein kinase 1 which belongs to the AGC family of kinases and is related in structure to the ribosomal p70 S6 kinase subfamily. MSK1 can be activated by ERK1/2 and SAPK2/p38 MAP kinase. It is also known to be required for the phosphorylation of CREB, ATF1 H3 and HMG14 in response to mitogen and stress. Similar to RSK, MSK1 contains two kinase domains (N term and a C term). Once phosphorylated on Thr581 and Ser360 by ERK1/2 and SAPK2/p38, MSK1 autophosphorylate on at least 5 sites. Of these autophosphorylation sites Ser212 and Ser376 get phosphorylated by the C terminal kinase domain of MSK1 which is essential for the catalytic activity of the N terminal kinase domain.

    基因ID
    9252
    途径
    MAPK Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
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