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CD11b 抗体 (AA 520-570)

Name: CD11b 抗体 (AA 520-570)
SKU: ABIN741285
Availability: OutOfStock

ITGAM 适用: 人, 小鼠, 大鼠 FACS 宿主: 兔 Polyclonal unconjugated

Human U937 cel CD11b/c Polyclonal Antibody, Unconjugated at 1:100 for 30 minutes followed by incubation with a PE Conjugated secondary (green) for 30 minutes compared to unstained control cells (blue), secondary only (light blue) and isotype control (orange). (CD11b 抗体 (AA 520-570))

FACS

Formalin-fixed and paraffin embedded rat kidney labeled with Rabbit Anti-CD11b/c Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (CD11b 抗体 (AA 520-570))

IHC (p)

Formalin-fixed and paraffin-embedded: human esophageal cancer labeled with Rabbit Anti-CD11C Polyclonal Antibody, Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining (CD11b 抗体 (AA 520-570))

IHC (p)

Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti Integrin Alpha X/CD11c Polyclonal Antibody, Unconjugated (ABIN741285) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (CD11b 抗体 (AA 520-570))

7 images

(4 references)

产品编号 ABIN741285

发货至: 中国

Datasheet as PDF

Key Features
- High quality CD11b Primary Antibody for the detection of ITGAM.
- Reliable product with high standard validation data
抗原 See all CD11b (ITGAM) 抗体

CD11b (ITGAM) (Integrin alpha M (ITGAM))
抗原表位
16

13

10

7

6

6

5

5

4

3

3

3

3

3

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 520-570
适用
252

161

59

33

17

17

16

14

11

7

7

4

4

2

2

1
人, 小鼠, 大鼠
宿主
134

103

102

2

1

1
兔
Compatible Secondaries
克隆类型
245

95

1
多克隆
标记
110

37

29

26

21

10

7

7

5

5

5

5

4

4

4

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This CD11b antibody is un-conjugated
应用范围
255

84

77

75

54

39

36

22

20

18

13

13

7

6

5

5

4

3

2

2

2

1

1
Flow Cytometry (FACS)

交叉反应

人, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CD11c

亚型

IgG

Product Specific Information

What can the CD11b Antibody ABIN741285 be used for?

This polyclonal CD11b Antibody detects CD11b. The CD11b Antibody has been validated for various applications and can be used for the detection of CD11b and derivatives by Flow Cytometry.

What validation data is available for this CD11b Antibody?

The Primary Antibody is referenced in 4 publications and is characterized by a proven, very high reliability. It has currently 7 product images that show its performance in a variety of applications. CD11b Antibody for the detection of CD11b and derivatives.

What is the function of CD11b?

This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 77-180) antibody
ITGAM 适用: 人, 小鼠, 大鼠 FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibody
ITGAM 适用: 人 FACS, WB, IHC (p) 宿主: 兔 Polyclonal RB17991 unconjugated

anti-Integrin alpha M (ITGAM) (AA 31-160) antibody
ITGAM 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM 适用: 人 IHC, WB, StM 宿主: 小鼠 Monoclonal ITGAM-3338 unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM 适用: 人 IHC, WB, StM 宿主: 小鼠 Monoclonal ITGAM-3340 unconjugated

anti-Integrin alpha M (ITGAM) antibody (Biotin)
ITGAM 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-174 Biotin

anti-Integrin alpha M (ITGAM) antibody (FITC)
ITGAM 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-174 FITC

anti-Integrin alpha M (ITGAM) antibody (PE)
ITGAM 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-174 PE

anti-Integrin alpha M (ITGAM) (AA 623-728) antibody
ITGAM 适用: 人 ELISA, ICC 宿主: 小鼠 Monoclonal 3A10H5 unconjugated

应用备注

WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C for 12 months.

有效期

12 months
Ju, Xing, Yang, Zheng, Jia, Zhang, Ren: "An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model." in: BMC immunology, Vol. 17, Issue 1, pp. 31, (2016) (PubMed).

Zhang, Wu, Hayashi, Okada, Nakanishi: "Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 8, pp. 3013-22, (2014) (PubMed).

Di Filippo, Rossi, Ferraro, Maisto, De Angelis, Ferraraccio, Rotondo, DAmico: "Involvement of proteasome and macrophages M2 in the protection afforded by telmisartan against the acute myocardial infarction in Zucker diabetic fatty rats with metabolic syndrome." in: Mediators of inflammation, Vol. 2014, pp. 972761, (2014) (PubMed).

Ahn, Ruiz, Barber: "Intrinsic self-DNA triggers inflammatory disease dependent on STING." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 9, pp. 4634-42, (2014) (PubMed).
抗原

CD11b (ITGAM) (Integrin alpha M (ITGAM))

别名

Cd11b/C (ITGAM 产品)

别名

CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody

背景

Synonyms: CD11C, SLEB6, Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p15,95 alpha chain, Leukocyte adhesion receptor p15,95, ITGAX
Background: Integrin alpha-X/beta-2 is a receptor for fibrinogen. It recognizes the sequence G-P-R in fibrinogen. It mediates cell-cell interaction during inflammatory responses. It is especially important in monocyte adhesion and chemotaxis.

基因ID

3687

UniProt

P20702

途径

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation