KISS1R 抗体 (AA 121-200)
-
- 抗原 See all KISS1R 抗体
- KISS1R (KISS1 Receptor (KISS1R))
-
抗原表位
- AA 121-200
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KISS1R antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Sheep,Pig,Guinea Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KiSS1 receptor
- 亚型
- IgG
- Top Product
- Discover our top product KISS1R Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
-
Leptin/leptinR-kisspeptin/kiss1r-GnRH pathway reacting to regulate puberty onset during negative energy balance." in: Life sciences, Vol. 153, pp. 207-12, (2016) (PubMed).
: "Expression of kisspeptin/kiss1r system in developing hypothalamus of female rat and the possible effects on reproduction development and maintenance." in: Journal of the Chinese Medical Association : JCMA, Vol. 79, Issue 10, pp. 546-53, (2016) (PubMed).
: "
-
Leptin/leptinR-kisspeptin/kiss1r-GnRH pathway reacting to regulate puberty onset during negative energy balance." in: Life sciences, Vol. 153, pp. 207-12, (2016) (PubMed).
-
- 抗原
- KISS1R (KISS1 Receptor (KISS1R))
- 别名
- Kiss1 Receptor (KISS1R 产品)
- 别名
- AXOR12 antibody, CPPB1 antibody, GPR54 antibody, HH8 antibody, HOT7T175 antibody, KISS-1R antibody, Gpr54 antibody, KiSS-1 antibody, gpr54 antibody, gpr54-1 antibody, gpr54a antibody, kiss1r antibody, kiss1rl antibody, kissr2 antibody, si:dkey-31m5.9 antibody, axor12 antibody, kissr1a antibody, KISS1 receptor antibody, KISS1 receptor a antibody, KISS1R antibody, Kiss1r antibody, kiss1ra antibody, kiss1r antibody
- 背景
-
Synonyms: HH8, CPPB1, GPR54, AXOR12, KISS-1R, HOT7T175, KiSS-1 receptor, G-protein coupled receptor 54, G-protein coupled receptor OT7T175, Hypogonadotropin-1, Kisspeptins receptor, Metastin receptor, KISS1R
Background: Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
- 基因ID
- 84634
- UniProt
- Q969F8
-