AVEN 抗体 (AA 301-362)
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- 抗原 See all AVEN 抗体
- AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
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抗原表位
- AA 301-362
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AVEN antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 预测反应
- Human,Mouse,Rat,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human AVEN
- 亚型
- IgG
- Top Product
- Discover our top product AVEN Primary Antibody
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anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 71-170) antibody
AVEN 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B10 unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 78-106), (N-Term) antibodyAVEN 适用: 人 WB 宿主: 兔 Polyclonal RB41905 unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 254-362) antibodyAVEN 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人, 猴 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人, 猴 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (AA 203-362) antibodyAVEN 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (N-Term) antibodyAVEN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Apoptosis, Caspase Activation Inhibitor (AVEN) (C-Term) antibodyAVEN 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- AVEN (Apoptosis, Caspase Activation Inhibitor (AVEN))
- 别名
- AVEN (AVEN 产品)
- 别名
- AVEN antibody, pdcd12 antibody, aven antibody, wu:fc08c09 antibody, si:ch211-150c22.4 antibody, PDCD12 antibody, 1700013A01Rik antibody, 1700056A21Rik antibody, mAven-L antibody, mAven-S antibody, apoptosis and caspase activation inhibitor antibody, apoptosis, caspase activation inhibitor L homeolog antibody, apoptosis, caspase activation inhibitor antibody, Aven antibody, AVEN antibody, aven.L antibody, aven antibody
- 背景
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Synonyms: 1700013A01Rik, 1700056A21Rik, mAven L, mAven S, MGC124011, Apoptosis caspase activation inhibitor, Cell death regulator Aven, OTTMUSP00000016129, PDCD12, Programmed cell death 12, RP23-52C15.2, AVEN_HUMAN
Background: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. AVEN is a recently discovered protein that blocks apoptosis induced by Apaf-1 and caspase-9. It is thought that AVEN functions by binding to Bcl-xL, an antiapoptotic member of the Bcl-2 family, and to Apaf-1, possibly interfering with the ability of Apaf-1 to self-associate, suggesting that AVEN impedes Apaf-1-mediated caspase activation. Higher levels of AVEN mRNA are seen in patients with acute leukemia than in control patients, suggesting that AVEN may be useful as a prognostic indicator in leukemia patients.
- 基因ID
- 57099
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