Integrin beta 3 抗体 (AA 27-120)
(6 references)-
- 抗原 See all Integrin beta 3 (ITGB3) 抗体
- Integrin beta 3 (ITGB3)
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抗原表位
- AA 27-120
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Integrin beta 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠
- 预测反应
- Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Integrin beta 3
- 亚型
- IgG
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anti-Integrin beta 3 (ITGB3) (AA 134-376) antibody
ITGB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) antibodyITGB3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 27-179) antibodyITGB3 适用: 人 FACS, IHC, ELISA 宿主: 小鼠 Monoclonal 3E8A6 unconjugated
anti-Integrin beta 3 (ITGB3) (AA 385-490) antibodyITGB3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGB3-2145 unconjugated
anti-Integrin beta 3 (ITGB3) antibody (FITC)ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 FITC
anti-Integrin beta 3 (ITGB3) antibody (PerCP)ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 PerCP
anti-Integrin beta 3 (ITGB3) (AA 610-718) antibodyITGB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 734-760) antibodyITGB3 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 135-377) antibodyITGB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (pTyr773) antibodyITGB3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells." in: Cells, Vol. 9, Issue 11, (2021) (PubMed).
: "Effect of 2,3',4,4',5-Pentachlorobiphenyl Exposure on Endometrial Receptivity and the Methylation of HOXA10." in: Reproductive sciences (Thousand Oaks, Calif.), Vol. 25, Issue 2, pp. 256-268, (2017) (PubMed).
: "High-Throughput RNAi Screening Identifies a Role for the Osteopontin Pathway in Proliferation and Migration of Human Aortic Smooth Muscle Cells." in: Cardiovascular drugs and therapy, Vol. 30, Issue 3, pp. 281-95, (2017) (PubMed).
: "Sophoricoside fails the embryo implantation by compromising the uterine endometrial receptivity at implantation "window" of pregnant mice." in: Chemico-biological interactions, Vol. 219C, pp. 57-63, (2014) (PubMed).
: "Induced apoptosis of osteoblasts proliferating on polyhydroxyalkanoates." in: Biomaterials, Vol. 34, Issue 15, pp. 3737-46, (2013) (PubMed).
: "Elevated expression of integrin αv and β5 subunit in laryngeal squamous-cell carcinoma associated with lymphatic metastasis and angiogenesis." in: Pathology, research and practice, Vol. 209, Issue 2, pp. 105-9, (2013) (PubMed).
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: "Amyloid-β Precursor Protein APP Down-Regulation Alters Actin Cytoskeleton-Interacting Proteins in Endothelial Cells." in: Cells, Vol. 9, Issue 11, (2021) (PubMed).
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- 抗原
- Integrin beta 3 (ITGB3)
- 别名
- Integrin beta 3 (ITGB3 产品)
- 别名
- BDPLT16 antibody, BDPLT2 antibody, CD61 antibody, GP3A antibody, GPIIIa antibody, GT antibody, INGRB3 antibody, integrin antibody, INTB3 antibody, GPIIIA antibody, cd61 antibody, gp3a antibody, itgb3 antibody, itgb3.2 antibody, itgb3.1 antibody, integrin subunit beta 3 antibody, integrin beta 3 antibody, integrin subunit beta 3 L homeolog antibody, integrin beta 3a antibody, integrin beta 3b antibody, ITGB3 antibody, Itgb3 antibody, itgb3.L antibody, itgb3a antibody, itgb3b antibody
- 背景
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Synonyms: GT, CD61, GP3A, BDPLT2, GPIIIa, BDPLT16, Integrin beta-3, Platelet membrane glycoprotein IIIa, ITGB3
Background: Integrin alpha-V/beta-3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. Integrins alpha-IIb/beta-3 and alpha-V/beta-3 recognize the sequence R-G-D in a wide array of ligands. Integrin alpha-IIb/beta-3 recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial surface. Fibrinogen binding enhances SELP expression in activated platelets (By similarity). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
- 分子量
- 87kDa
- 基因ID
- 3690
- UniProt
- P05106
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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