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TRAF6 抗体 (AA 441-530)

Name: TRAF6 抗体 (AA 441-530)
SKU: ABIN738906
Availability: OutOfStock

TRAF6 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human oral squamous cell carcinoma labeled with Anti-TRAF6 Polyclonal Antibody, Unconjugated (ABIN738906) followed by conjugation to the secondary antibody and DAB staining (TRAF6 抗体 (AA 441-530))

IHC

1 image

(1 reference)

产品编号 ABIN738906

发货至: 中国

Datasheet as PDF

抗原 See all TRAF6 抗体

TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))
抗原表位
14

9

8

5

2

2

1

1

1

1

1

1

1

1

1

1
AA 441-530
适用
66

36

31

14

5

5

5

3

2

2

1
人, 小鼠, 大鼠, 小鸡
宿主
64

4

2
兔
Compatible Secondaries
克隆类型
65

5
多克隆
标记
35

4

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This TRAF6 antibody is un-conjugated
应用范围
54

16

12

12

12

10

10

7

6

2

1

1

1

1

1
Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

小鸡, 人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse TRAF6

亚型

IgG

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anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 263-522) antibody
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anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibody
TRAF6 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 1-522) antibody
TRAF6 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-TNF Receptor-Associated Factor 6 (TRAF6) (C-Term) antibody
TRAF6 适用: 人, 小鼠 WB, IHC, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-TNF Receptor-Associated Factor 6 (TRAF6) (AA 254-475) antibody
TRAF6 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 5843, (2017) (PubMed).
抗原

TRAF6 (TNF Receptor-Associated Factor 6 (TRAF6))

别名

TRAF6 (TRAF6 产品)

别名

MGC:3310 antibody, RNF85 antibody, 2310003F17Rik antibody, AI851288 antibody, C630032O20Rik antibody, rnf85 antibody, traf6 antibody, xtraf6 antibody, CG10961 antibody, DTRAF2 antibody, Dmel\\CG10961 antibody, TRAF antibody, TRAF2 antibody, TRAF6 antibody, Traf2 antibody, dTRAF2 antibody, dTRAF6 antibody, dTraf2 antibody, dtraf2 antibody, GB10539 antibody, fi15f02 antibody, wu:fi15f02 antibody, zgc:63704 antibody, TNF receptor associated factor 6 antibody, TNF receptor-associated factor 6 antibody, TNF receptor associated factor 6 L homeolog antibody, TNF-receptor-associated factor 6 antibody, TNF receptor associated factor 6 S homeolog antibody, TRAF6 antibody, Traf6 antibody, traf6.L antibody, traf6 antibody, LOC551819 antibody, traf6.S antibody

背景

Synonyms: AI851288, 2310003F17Rik, C630032O20Rik, TNF receptor-associated factor 6, E3 ubiquitin-protein ligase TRAF6, Traf6
Background: E3 ubiquitin ligase that, together with UBE2N and UBE2V1, mediates the synthesis of 'Lys-63'-linked-polyubiquitin chains conjugated to proteins, such as IKBKG, IRAK1, AKT1 and AKT2. Also mediates ubiquitination of free/unanchored polyubiquitin chain that leads to MAP3K7 activation (By similarity). Leads to the activation of NF-kappa-B and JUN. May be essential for the formation of functional osteoclasts. Seems to also play a role in dendritic cells (DCs) maturation and/or activation. Represses c-Myb-mediated transactivation, in B-lymphocytes. Adapter protein that seems to play a role in signal transduction initiated via TNF receptor, IL-1 receptor and IL-17 receptor. Regulates osteoclast differentiation by mediating the activation of adapter protein complex 1 (AP-1) and NF-kappa-B, in response to RANK-L stimulation. Together with MAP3K8, mediates CD40 signals that activate ERK in B-cells and macrophages, and thus may play a role in the regulation of immunoglobulin production.

基因ID

22034

UniProt

P70196

途径

NF-kappaB Signaling, TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Hepatitis C, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway