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SSTR2 抗体 (AA 211-320)

SSTR2 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN738216
发货至: 中国
  • 抗原 See all SSTR2 抗体
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    抗原表位
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 211-320
    适用
    • 42
    • 24
    • 23
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠
    宿主
    • 38
    • 4
    克隆类型
    • 37
    • 4
    • 1
    多克隆
    标记
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SSTR2 antibody is un-conjugated
    应用范围
    • 19
    • 14
    • 12
    • 7
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SSTR2
    亚型
    IgG
    Top Product
    Discover our top product SSTR2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Sakai, Yonezawa, Yamawaki, Oyamada: "Alteration of somatostatin receptor 2 expression in canine mammary gland tumor." in: The Journal of veterinary medical science / the Japanese Society of Veterinary Science, (2015) (PubMed).

    Ruan, Yu, Xu, Zhang, Long, Shen: "Attenuation of stress-induced gastrointestinal motility disorder by gentiopicroside, from Gentiana macrophylla Pall." in: Fitoterapia, Vol. 103, pp. 265-76, (2015) (PubMed).

  • 抗原
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    别名
    SSTR2/Somatostatin Receptor 2 (SSTR2 产品)
    别名
    Smstr2 antibody, SSTR-2 antibody, Smstr-2 antibody, sst2 antibody, SS2R antibody, SSTR2 antibody, MGC80373 antibody, somatostatin receptor 2 antibody, somatostatin receptor 2 L homeolog antibody, SSTR2 antibody, Sstr2 antibody, sstr2.L antibody
    背景

    Synonyms: Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SRIF-1, SSTR2

    Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    基因ID
    6752
    UniProt
    P30874
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