我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

LGR5 抗体 (AA 810-907)

Name: LGR5 抗体 (AA 810-907)
SKU: ABIN737916
Availability: OutOfStock

LGR5 适用: 人, 小鼠 WB, FACS, ELISA, IHC (p), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-GPR49/LGR5 Polyclonal Antibody, Unconjugated (ABIN737916) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (LGR5 抗体 (AA 810-907))

IHC

Formalin-fixed and paraffin embedded mouse colon carcinoma labeled with Anti-GPR49/LGR5 Polyclonal Antibody, Unconjugated (ABIN737916) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (LGR5 抗体 (AA 810-907))

IHC

Formalin-fixed and paraffin embedded mouse colon carcinoma labeled with Anti-GPR49/LGR5 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (LGR5 抗体 (AA 810-907))

IHC (p)

Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-GPR49/LGR5 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining. (LGR5 抗体 (AA 810-907))

IHC (p)

MCF-7 cells probed with GPR49/LGR5 Polyclonal Antibody, unconjugated at 1:100 dilution for 30 minutes compared to control cells (blue) and isotype control (orange) (LGR5 抗体 (AA 810-907))

5 images

(1 reference)

产品编号 ABIN737916

发货至: 中国

Datasheet as PDF

抗原 See all LGR5 抗体

LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))
抗原表位
16

15

8

7

7

5

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 810-907
适用
98

56

49

1

1
人, 小鼠
宿主
86

13
兔
Compatible Secondaries
克隆类型
77

22
多克隆
标记
45

6

4

4

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This LGR5 antibody is un-conjugated
应用范围
71

37

19

19

17

17

13

13

7

6

2

1

1

1
Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠

预测反应

Rat,Dog,Cow,Sheep,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse GPR49

亚型

IgG
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibody
LGR5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB14555 unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 22-178) antibody
LGR5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B5B9 unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibody
LGR5 适用: 人, 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal RB14211 unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 689-719) antibody
LGR5 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 443-473) antibody
LGR5 适用: 人 WB, FACS, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 250-550) antibody
LGR5 适用: 人, 小鼠 WB, FACS, IHC, IF, IP 宿主: 小鼠 Monoclonal 2A2 unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (Cytoplasmic Domain) antibody
LGR5 适用: 人 IHC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 824-907) antibody
LGR5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) (AA 241-352) antibody
LGR5 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5) antibody
LGR5 适用: 人 WB, FACS, ELISA 宿主: 兔 Monoclonal 4H8 unconjugated Recombinant Antibody

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Su, Li, Liu, Ren, Tian, Liu, Qiu: "Ionizing radiation promotes advanced malignant traits in nasopharyngeal carcinoma via activation of epithelial-mesenchymal transition and the cancer stem cell phenotype." in: Oncology reports, Vol. 36, Issue 1, pp. 72-8, (2016) (PubMed).
抗原

LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

别名

GPR49/LGR5 (LGR5 产品)

别名

lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody

背景

Synonyms: FEX, Gpr49, Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, Orphan G-protein coupled receptor FEX, Lgr5
Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.

基因ID

14160

UniProt

Q9Z1P4

途径

WNT signaling