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MYD88 抗体 (AA 201-296)

Name: MYD88 抗体 (AA 201-296)
SKU: ABIN736881
Availability: OutOfStock

MYD88 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IP, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Mice were anesthetized and then infected intranasally by dropping 0. (MYD88 抗体 (AA 201-296))

Formalin-fixed and paraffin embedded mouse lung tissue labeled with Anti-MyD88 Polyclonal Antibody, Unconjugated (ABIN736881) at 1:200, followed by conjugation to the secondary antibody and DAB staining (MYD88 抗体 (AA 201-296))

IHC

Formalin-fixed and paraffin embedded mouse lung tissue labeled with Anti-MyD88 Polyclonal Antibody, Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining (MYD88 抗体 (AA 201-296))

IHC (p)

Molt-4 lysates probed with MyD88 Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (MYD88 抗体 (AA 201-296))

5 images

(6 references)

产品编号 ABIN736881

发货至: 中国

Datasheet as PDF

抗原 See all MYD88 抗体

MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
抗原表位
14

8

7

5

5

4

4

4

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 201-296
适用
95

61

49

15

7

5

5

5

4

4

4

2

1

1

1
人, 小鼠, 大鼠, 小鸡
宿主
87

13

2
兔
Compatible Secondaries
克隆类型
80

22
多克隆
标记
62

7

5

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
This MYD88 antibody is un-conjugated
应用范围
83

31

25

15

13

13

12

12

11

10

3

2

2

1

1
Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

小鸡, 人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse MyD88

亚型

IgG
anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 32-265) antibody
MYD88 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (Internal Region) antibody
Verified MYD88 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 44-264) antibody
MYD88 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibody
MYD88 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 136-164) antibody
MYD88 适用: 人, 小鼠 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibody
MYD88 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 1-296) antibody
MYD88 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibody
MYD88 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) (AA 60-309) antibody
MYD88 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Myeloid Differentiation Primary Response Gene (88) (MYD88) antibody
KO Validated MYD88 适用: 人 WB 宿主: 兔 Monoclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Fu, Xia, Liu, Wang, Wang, Shi, Song, Song, Song et al.: "The acute exposure of tetrachloro-p-benzoquinone (a.k.a. chloranil) triggers inflammation and neurological dysfunction via Toll-like receptor 4 signaling: The protective role of melatonin ..." in: Toxicology, Vol. 381, pp. 39-50, (2017) (PubMed).

Li, Yu, Li, Liu, Jiao, Song, Lv, Qin: "Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 5843, (2017) (PubMed).

Fu, Shi, Song, Liu, Wang, Wang, Song, Song: "From the Cover: Tetrachlorobenzoquinone Exerts Neurological Proinflammatory Activity by Promoting HMGB1 Release, Which Induces TLR4 Clustering within the Lipid Raft." in: Toxicological sciences : an official journal of the Society of Toxicology, Vol. 153, Issue 2, pp. 303-15, (2016) (PubMed).

Chen, Ye, Zhang, Tang, Li, Lu, Wu, Yu, Kou: "Limb Remote Ischemic Postconditioning Reduces Ischemia-Reperfusion Injury by Inhibiting NADPH Oxidase Activation and MyD88-TRAF6-P38MAP-Kinase Pathway of Neutrophils." in: International journal of molecular sciences, Vol. 17, Issue 12, (2016) (PubMed).

Wang, Shi, Lv, Xu, Li, Ge, Xiao, Geng, Liu: "Artesunate Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Suppressing TLR4, MyD88 Expression, and NF-?B Activation in Microglial Cells." in: Inflammation, (2015) (PubMed).

Lu, Liu, Gu, Ge, Wu, Ze-Ji, Qiu, Zhang, Chao, Yu: "Gene Expression Profiles Underlying Selective T-Cell-Mediated Immunity Activity of a Chinese Medicine Granule on Mice Infected with Influenza Virus H1N1." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 976364, (2014) (PubMed).
抗原

MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))

别名

MyD88 (MYD88 产品)

别名

MYD88D antibody, XMyD88 antibody, myd88d antibody, MGC84928 antibody, CG2078 antibody, DMMYD88 antibody, DmMyD88 antibody, DmMyd88 antibody, Dmel\\CG2078 antibody, EP(2)2535 antibody, Kra antibody, LD20892 antibody, MYD88 antibody, MyD88 antibody, Myd88F antibody, dMyD88 antibody, dMyd88 antibody, kra antibody, myd88 antibody, zgc:103541 antibody, GB12344 antibody, NV10640 antibody, myd88-a antibody, myd88-b antibody, myeloid differentiation primary response 88 antibody, myeloid differentiation primary response 88 S homeolog antibody, myeloid differentiation primary response gene 88 antibody, CG2078 gene product from transcript CG2078-RB antibody, myeloid differentiation primary response protein MyD88-A antibody, myeloid differentiation primary response protein MyD88 antibody, myeloid differentiation factor 88 antibody, myeloid differentiation primary response 88 L homeolog antibody, MYD88 antibody, myd88.S antibody, Myd88 antibody, myd88 antibody, LOC413194 antibody, LOC100118553 antibody, LOC575153 antibody, myd88.L antibody

背景

Synonyms: Myeloid differentiation primary response protein MyD88, Myd88
Background: Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Increases IL-8 transcription. Involved in IL-18-mediated signaling pathway. Isoform 2 is defective in its ability to induce IRAK phosphorylation and NF-kappa-B activation and can function as a negative regulator of activation by IL-1 or lipopolysaccharide (LPS). Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. MyD88-mediated signaling in intestinal epithelial cells is crucial for maintenance of gut homeostasis and controls the expression of the antimicrobial lectin REG3G in the small intestine.

基因ID

17874

UniProt

P22366

途径

NF-kappaB Signaling, TLR signaling, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades