Prosaposin 抗体 (AA 101-200)
Quick Overview for Prosaposin 抗体 (AA 101-200) (ABIN735773)
抗原
See all Prosaposin (PSAP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PSAP
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亚型
- IgG
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anti-Prosaposin (PSAP) (AA 325-524) antibody
PSAP 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 4D5F4 unconjugated
anti-Prosaposin (PSAP) (AA 17-524) antibodyPSAP 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 60-310) antibodyPSAP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 17-216) antibodyPSAP 适用: 人, 大鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3B4A8 unconjugated
anti-Prosaposin (PSAP) (AA 18-524) antibodyPSAP 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1D1-C12 unconjugated
anti-Prosaposin (PSAP) (AA 325-524) antibodyPSAP 适用: 人 WB, IHC, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Prosaposin (PSAP) (AA 311-391) antibodyPSAP 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) (AA 1-524) antibodyPSAP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F6 unconjugated
anti-Prosaposin (PSAP) (Internal Region) antibodyPSAP 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Prosaposin (PSAP) antibodyPSAP 适用: 人 IHC 宿主: 小鼠 Monoclonal MSVA-452M unconjugated Recombinant Antibody
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- Prosaposin (PSAP)
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别名
- PSAP/PAP
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背景
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Synonyms: GLBA, SAP1, Prosaposin, Proactivator polypeptide, PSAP
Background: Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-B stimulates the hydrolysis of galacto-cerebroside sulfate by arylsulfatase A (EC 3.1.6.8), GM1 gangliosides by beta-galactosidase (EC 3.2.1.23) and globotriaosylceramide by alpha-galactosidase A (EC 3.2.1.22). Saposin-B forms a solubilizing complex with the substrates of the sphingolipid hydrolases. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.
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基因ID
- 5660
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UniProt
- P07602
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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