Cytokeratin 1 抗体 (AA 141-240)
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- 抗原 See all Cytokeratin 1 (KRT1) 抗体
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
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抗原表位
- AA 141-240
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适用
- 人, 小鼠, 大鼠, Cow
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cytokeratin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- Cow, 人, 小鼠, 大鼠
- 预测反应
- Dog,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human pan cytokeratin
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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lncRNA H19 is involved in TGF-β1-induced epithelial to mesenchymal transition in bovine epithelial cells through PI3K/AKT Signaling Pathway." in: PeerJ, Vol. 5, pp. e3950, (2017) (PubMed).
: "Anti-proliferative activities of finasteride in benign prostate epithelial cells require stromal fibroblasts and c-Jun gene." in: PLoS ONE, Vol. 12, Issue 2, pp. e0172233, (2017) (PubMed).
: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).
: "Identification of apoptotic cells in the thymus of piglets infected with highly pathogenic porcine reproductive and respiratory syndrome virus." in: Virus research, Vol. 189, pp. 29-33, (2014) (PubMed).
: "Enrichment of Oct3/4-positive cells from a human bronchial epithelial cell line." in: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, Vol. 121, Issue 7, pp. 612-25, (2013) (PubMed).
: "
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lncRNA H19 is involved in TGF-β1-induced epithelial to mesenchymal transition in bovine epithelial cells through PI3K/AKT Signaling Pathway." in: PeerJ, Vol. 5, pp. e3950, (2017) (PubMed).
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- 抗原
- Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
- 别名
- Cytokeratin (KRT1 产品)
- 别名
- CK1 antibody, EHK antibody, EHK1 antibody, EPPK antibody, K1 antibody, KRT1A antibody, NEPPK antibody, Krt-2.1 antibody, Krt2-1 antibody, Krt86 antibody, KRT1 antibody, Kb1 antibody, KER1 antibody, CK-1 antibody, Keratin-1 antibody, keratin 1 antibody, KRT1 antibody, Krt1 antibody
- 背景
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Synonyms: pan-cytokeratin, pan-CK, pan CK, P-CK, wide spectrum Cytokeratin, Cytokeratins, [cytokeratins 1, 2,4,5,6,7,8,71,72,75,78].
Background: Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The cytokeratins are encoded by a family encompassing 30 genes. Among them, 20 are epithelial genes and the remaining 10 are specific for trichocytes. In the cytoplasm, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane. Numerous accessory proteins are involved in the genesis and maintenance of such structure. This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms. Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, cell movement and differentiation. Cytokeratins interact with desmosomes and hemidesmosomes, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection.
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