CXCR1 抗体 (AA 186-280)
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- 抗原 See all CXCR1 抗体
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
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抗原表位
- AA 186-280
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CXCR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Cow,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human CXCR1
- 亚型
- IgG
- Top Product
- Discover our top product CXCR1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks lung inflammation in swine barn dust-instilled mice." in: Pulmonary pharmacology & therapeutics, Vol. 31, pp. 55-62, (2015) (PubMed).
: "Role of GPER1, EGFR and CXCR1 in differentiating between malignant follicular thyroid carcinoma and benign follicular thyroid adenoma." in: International journal of clinical and experimental pathology, Vol. 8, Issue 9, pp. 11236-47, (2015) (PubMed).
: "High expression of GPER1, EGFR and CXCR1 is associated with lymph node metastasis in papillary thyroid carcinoma." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3213-23, (2015) (PubMed).
: "Effects of vitamin D on renal fibrosis in diabetic nephropathy model rats." in: International journal of clinical and experimental pathology, Vol. 7, Issue 6, pp. 3028-37, (2014) (PubMed).
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CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks lung inflammation in swine barn dust-instilled mice." in: Pulmonary pharmacology & therapeutics, Vol. 31, pp. 55-62, (2015) (PubMed).
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- 抗原
- CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))
- 别名
- CXCR1 (CXCR1 产品)
- 别名
- C-C antibody, C-C-CKR-1 antibody, CD128 antibody, CD181 antibody, CDw128a antibody, CKR-1 antibody, CMKAR1 antibody, IL8R1 antibody, IL8RA antibody, IL8RBA antibody, Il8ra antibody, CXCR-1 antibody, IL-8RA antibody, CXCR2 antibody, IL8RB antibody, cxcr1 antibody, cxcr2 antibody, C-X-C motif chemokine receptor 1 antibody, chemokine (C-X-C motif) receptor 1 antibody, C-X-C chemokine receptor type 1 antibody, C-X-C motif chemokine receptor 1 S homeolog antibody, CXCR1 antibody, Cxcr1 antibody, LOC100461947 antibody, cxcr1.S antibody
- 背景
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Synonyms: C-C, CD128, CD181, CKR-1, IL8R1, IL8RA, CMKAR1, IL8RBA, CDw128a, C-C-CKR-1, C-X-C chemokine receptor type 1, CXC-R1, CXCR-1, High affinity interleukin-8 receptor A, IL-8R A, IL-8 receptor type 1, CXCR1
Background: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.
- 基因ID
- 3577
- UniProt
- P25024
- 途径
- cAMP Metabolic Process
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