PDX1 抗体 (AA 188-284)
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- 抗原 See all PDX1 抗体
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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抗原表位
- AA 188-284
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适用
- 大鼠, 山羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PDX1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 山羊, 大鼠
- 预测反应
- Human,Mouse,Pig,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from mouse PDX1
- 亚型
- IgG
- Top Product
- Discover our top product PDX1 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Effect of Wnt Signaling on the Differentiation of Islet β-Cells from Adipose-Derived Stem Cells." in: BioMed research international, Vol. 2017, pp. 2501578, (2017) (PubMed).
: "The Modification of Tet1 in Male Germline Stem Cells and Interact with PCNA, HDAC1 to promote their Self-renewal and Proliferation." in: Scientific reports, Vol. 6, pp. 37414, (2016) (PubMed).
: "Generation of insulin-producing cells from C3H10T1/2 mesenchymal progenitor cells." in: Gene, Vol. 562, Issue 1, pp. 107-16, (2015) (PubMed).
: "Morphological Characteristics and Identification of Islet-like Cells Derived From Rat Adipose-derived Stem Cells Cocultured with Pancreas Adult Stem Cells." in: Cell biology international, (2014) (PubMed).
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Effect of Wnt Signaling on the Differentiation of Islet β-Cells from Adipose-Derived Stem Cells." in: BioMed research international, Vol. 2017, pp. 2501578, (2017) (PubMed).
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- 抗原
- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
- 别名
- PDX1 (PDX1 产品)
- 别名
- GSF antibody, IDX-1 antibody, IPF1 antibody, IUF1 antibody, MODY4 antibody, PDX-1 antibody, STF-1 antibody, ipf1 antibody, PDX1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, pdx-1 antibody, Idx1 antibody, Stf1 antibody, zgc:100874 antibody, XlHbox-8 antibody, xlhbox8 antibody, pancreatic and duodenal homeobox 1 antibody, pancreatic and duodenal homeobox 1 S homeolog antibody, PDX1 antibody, pdx1 antibody, Pdx1 antibody, pdx1.S antibody
- 背景
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Synonyms: Ipf1, IDX-1, IPF-1, Mody4, STF-1, pdx-1, Pancreas/duodenum homeobox protein 1, Insulin promoter factor 1, Islet/duodenum homeobox 1, Somatostatin-transactivating factor 1, Pdx1
Background: Activates insulin and somatostatin gene transcription. Key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds the DNA sequence 5'-CC[CT]TAATGGG-3'.
- 基因ID
- 18609
- UniProt
- P52946
- 途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
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