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Glutathione Reductase 抗体 (AA 421-522)

GSR 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN728848
发货至: 中国
  • 抗原 See all Glutathione Reductase (GSR) 抗体
    Glutathione Reductase (GSR)
    抗原表位
    • 15
    • 14
    • 10
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 421-522
    适用
    • 57
    • 26
    • 20
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 75
    • 8
    克隆类型
    • 76
    • 7
    多克隆
    标记
    • 33
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glutathione Reductase antibody is un-conjugated
    应用范围
    • 54
    • 30
    • 27
    • 25
    • 25
    • 21
    • 15
    • 10
    • 9
    • 8
    • 5
    • 4
    • 2
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    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GSR
    亚型
    IgG
    Top Product
    Discover our top product GSR Primary Antibody
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Khan, Li, Ahmad Khan, Rasul, Nawaz, Sun, Zheng, Ma: "Alantolactone induces apoptosis in HepG2 cells through GSH depletion, inhibition of STAT3 activation, and mitochondrial dysfunction." in: BioMed research international, Vol. 2013, pp. 719858, (2013) (PubMed).

  • 抗原
    Glutathione Reductase (GSR)
    别名
    GLUR/glutathione reductase (GSR 产品)
    别名
    GR antibody, ATGR2 antibody, EMB2360 antibody, glutathione reductase antibody, AI325518 antibody, D8Ertd238e antibody, Gr-1 antibody, Gr1 antibody, DDBDRAFT_0168952 antibody, DDBDRAFT_0231410 antibody, DDB_0168952 antibody, DDB_0231410 antibody, 2151 antibody, CG2151 antibody, DTR antibody, Dm-TrxR antibody, DmTR antibody, DmTrx antibody, DmTrxR antibody, DmTrxR-1 antibody, Dmel\\CG2151 antibody, Gr antibody, Trx antibody, TrxR antibody, TrxR-1 antibody, Trxr1 antibody, anon-WO03040301.185 antibody, anon-WO03040301.187 antibody, dTrxR antibody, dmtrxr-1 antibody, gr antibody, l(1)G0154 antibody, l(1)G0379 antibody, l(1)G0477 antibody, l(1)G0481 antibody, trxr-1 antibody, gor1 antibody, glutathione reductase, gro-2 antibody, glutathione reductase antibody, glutathione-disulfide reductase antibody, GR; GRase antibody, mitochondrial glutathione reductase Pgr1 antibody, Glutathione reductase (GR) (GRase) antibody, Thioredoxin reductase-1 antibody, glutathione-disulfide reductase family protein antibody, glutathione reductase 1 antibody, GR antibody, gor antibody, GSR antibody, GSR1 antibody, Gsr_2 antibody, Gsr antibody, GSHR1 antibody, gsr antibody, LbGR antibody, pgr1 antibody, GSHR2 antibody, GLR2 antibody, Bcen_2392 antibody, RPE_1989 antibody, HCAG_02219 antibody, SJAG_01162 antibody, Trxr-1 antibody, PF14_0192 antibody, POPTR_0001s14480g antibody, gsr1 antibody
    背景

    Synonyms: glutathione reductase, GLUR, Glutathione reductase mitochondrial, GR, Gr1, GRase, GRD 1, GRD1, GSR, MGC78522.

    Background: Glutathione reductase (GR) is a member of pyridine nucleotide- disulfideoxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG): GSSG + NADPH + H+?2GSH + NADP+. In mosteukaryotic cells, GR maintains the ratio of [GSH]/[GSSG], and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.

    基因ID
    2890
    途径
    Thyroid Hormone Synthesis, Cell RedoxHomeostasis
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