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CD31 抗体 (AA 681-738)

Name: CD31 抗体 (AA 681-738)
SKU: ABIN726140
Availability: OutOfStock

PECAM1 适用: 人, 小鼠, 大鼠, 兔, Pig, Cow FACS, WB, ELISA, IHC (p), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated

U937 lysates probed with CD31 Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (CD31 抗体 (AA 681-738))

Formalin-fixed and paraffin embedded rabbit sclera tissue labeled with Rabbit Anti-CD31/PECAM-1 Polyclonal Antibody (ABIN726140) at 1:600 followed by conjugation to the secondary antibody and DAB staining. (CD31 抗体 (AA 681-738))

IHC

3 images

(29 references)

产品编号 ABIN726140

发货至: 中国

Datasheet as PDF

抗原 See all CD31 (PECAM1) 抗体

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
抗原表位
16

16

15

12

8

8

7

6

5

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 681-738
适用
262

131

70

58

40

28

21

17

7

4

4

3

2

1

1

1
人, 小鼠, 大鼠, 兔, Pig, Cow
宿主
148

145

41

6

3

2
兔
Compatible Secondaries
克隆类型
214

130

1
多克隆
标记
151

30

29

24

13

5

5

5

5

5

5

5

5

5

5

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
This CD31 antibody is un-conjugated
应用范围
217

181

97

95

59

36

35

31

25

25

16

15

13

9

6

5

3

2

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

交叉反应

Cow, 人, 小鼠, Pig, 兔, 大鼠

预测反应

Dog,Sheep

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CD31

亚型

IgG

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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (C-Term) antibody
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 28-315) antibody
PECAM1 适用: 人 FACS, WB, IHC, IF, ELISA 宿主: 小鼠 Monoclonal 9E6E12 unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 29-738) antibody
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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 适用: 人, 兔, Cynomolgus FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal JC-70A unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 适用: 人, 大鼠 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal C31-3 unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) (AA 625-738) antibody
PECAM1 适用: 人 FACS, IHC, IF, StM 宿主: 小鼠 Monoclonal PECAM1-3527 unconjugated

anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 适用: 人, 大鼠, 兔, Cynomolgus FACS, WB, IHC, StM 宿主: 小鼠 Monoclonal C31-7 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Kong, Lee, Youm, Kim, Lee, Suh, Kim: "Effect of treatment with angiopoietin-2 and vascular endothelial growth factor on the quality of xenografted bovine ovarian tissue in mice." in: PLoS ONE, Vol. 12, Issue 9, pp. e0184546, (2018) (PubMed).

Brumm, Nunez, Doroudchi, Kawaguchi, Duan, Pellegrini, Lam, Carmichael, Deb, Hinman: "Astrocytes Can Adopt Endothelial Cell Fates in a p53-Dependent Manner." in: Molecular neurobiology, Vol. 54, Issue 6, pp. 4584-4596, (2018) (PubMed).

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Wu, Zhang, Ye, Shen, Liu, Hu, Li, Wu, Chen, Zhou: "Overexpression and correlation of HIF-2α, VEGFA and EphA2 in residual hepatocellular carcinoma following high-intensity focused ultrasound treatment: Implications for tumor recurrence and progression." in: Experimental and therapeutic medicine, Vol. 13, Issue 6, pp. 3529-3534, (2017) (PubMed).

Yang, Pei, Wang, Jin, Yu, Zhou, Zhang, Zhang, Lin: "Tiamulin inhibits breast cancer growth and pulmonary metastasis by decreasing the activity of CD73." in: BMC cancer, Vol. 17, Issue 1, pp. 255, (2017) (PubMed).

Schuerlein, Schwarz, Krziminski, Gätzner, Hoppensack, Schwedhelm, Schweinlin, Walles, Hansmann: "A versatile modular bioreactor platform for Tissue Engineering." in: Biotechnology journal, (2016) (PubMed).

Struecker, Hillebrandt, Raschzok, Jöhrens, Butter, Tang, Andreou, Napierala, Reutzel-Selke, Denecke, Pratschke, Sauer: "Implantation of a Tissue-Engineered Neo-Bile Duct in Domestic Pigs." in: European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes, Vol. 56, Issue 1-2, pp. 61-75, (2016) (PubMed).

Ji, Zhang, Chen, Che, Zhou, Wang: "Sodium humate accelerates cutaneous wound healing by activating TGF-β/Smads signaling pathway in rats." in: Acta pharmaceutica Sinica. B, Vol. 6, Issue 2, pp. 132-40, (2016) (PubMed).

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Xiang, Zheng, Zhou, Qiao, Tran, Pu, Li, Kong, Kouzani, Lin, Liu, Li, Shigdar, Duan: "Superior Performance of Aptamer in Tumor Penetration over Antibody: Implication of Aptamer-Based Theranostics in Solid Tumors." in: Theranostics, Vol. 5, Issue 10, pp. 1083-97, (2015) (PubMed).

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抗原

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

别名

CD31 (PECAM1 产品)

别名

CD31 antibody, CD31/EndoCAM antibody, GPIIA' antibody, PECA1 antibody, PECAM-1 antibody, endoCAM antibody, C85791 antibody, Cd31 antibody, Pecam antibody, platelet/endothelial cell adhesion molecule 1 antibody, platelet and endothelial cell adhesion molecule 1 antibody, pecam1 antibody, PECAM1 antibody, Pecam1 antibody

背景

Synonyms: CD31, PECA1, GPIIA', PECAM-1, endoCAM, CD31/EndoCAM, Platelet endothelial cell adhesion molecule, PECAM1
Background: Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-69 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).

基因ID

5175

UniProt

P16284

途径

Regulation of Actin Filament Polymerization