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PIK3R1 抗体 (AA 501-600)

Name: PIK3R1 抗体 (AA 501-600)
SKU: ABIN725405
Availability: OutOfStock

PI3K p85a 适用: 人, 小鼠, 大鼠, 兔 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain labeled with Anti-PI3K/PI3 kinase p85 alpha subunit Polyclonal Antibody, Unconjugated (ABIN725405) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (PIK3R1 抗体 (AA 501-600))

IHC

Formalin-fixed and paraffin embedded human endometrium carcinoma labeled with Anti-PI3K/PI3 kinase p85 alpha subunit Polyclonal Antibody, Unconjugated (ABIN725405) at 1:200 followed by conjugation to the secondary antibody and DAB staining. (PIK3R1 抗体 (AA 501-600))

IHC

Rat brain lysates probed with Anti PI3K/PI3 kinase p85 alpha subunit Polyclonal Antibody, Unconjugated (ABIN725405) at 1:200 in 4 °C. (PIK3R1 抗体 (AA 501-600))

SDS

H9C2 cells probed with Rabbit Anti-PI3 kinase p85 alpha subunit Polyclonal Antibody (PIK3R1 抗体 (AA 501-600))

FACS

HepG2 cells were stained with PI3 kinase p85 alpha subunit Polyclonal Antibody, Unconjugated at 1:500 in PBS and incubated for two hours at 37°C followed by Goat Anti-Rabbit IgG (H+L) Cy3 conjugated secondary antibody. (PIK3R1 抗体 (AA 501-600))

IF (cc)

5 images

(7 references)

产品编号 ABIN725405

发货至: 中国

Datasheet as PDF

抗原 See all PIK3R1 (PI3K p85a) 抗体

PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))
抗原表位
19

16

15

13

13

12

8

5

5

5

4

4

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 501-600
适用
129

93

66

18

17

6

3

3

3

2

2

2

2

1

1
人, 小鼠, 大鼠, 兔
宿主
115

29
兔
Compatible Secondaries
克隆类型
105

39
多克隆
标记
72

11

10

7

5

5

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2
This PIK3R1 antibody is un-conjugated
应用范围
117

57

39

27

23

16

16

12

12

5

5

2

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 兔, 大鼠

预测反应

Dog,Cow,Horse,Chicken

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human PI3 kinase p85 subunit alpha

亚型

IgG

Top Product

Discover our top product PI3K p85a Primary Antibody
anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-454) antibody
PI3K p85a 适用: 人 WB, ELISA, IP, PLA 宿主: 小鼠 Monoclonal 3A10 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr607) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠, Pig WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibody
PI3K p85a 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 6G10 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-30), (N-Term) antibody
PI3K p85a 适用: 人, 大鼠 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB11634 unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 159-388) antibody
PI3K p85a 适用: 人, 小鼠 WB, ELISA, IHC, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (pTyr607) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 15-180) antibody
PI3K p85a 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (AA 1-424) antibody
PI3K p85a 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) antibody
PI3K p85a 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a) (C-Term) antibody
PI3K p85a 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Wang, Wang, Zhang, Lin, Liu, Xiao, Xiao, Wang: "Defective insulin signaling and the protective effects of dimethyldiguanide during follicular development in the ovaries of polycystic ovary syndrome." in: Molecular medicine reports, Vol. 16, Issue 6, pp. 8164-8170, (2017) (PubMed).

An, Lv, Tian, He, Ling: "Role of the PTEN/PI3K/VEGF pathway in the development of Kawasaki disease." in: Experimental and therapeutic medicine, Vol. 11, Issue 4, pp. 1318-1322, (2016) (PubMed).

Sun, Yang, Luo, Wang, Chen, Zhang, Wang, Li: "Thyroid hormone inhibits the proliferation of piglet Sertoli cell via PI3K signaling pathway." in: Theriogenology, (2014) (PubMed).

Yang, Hui, Yuqin, Jie, Shuai, Tiezhu, Wei: "Effect of saw palmetto extract on PI3K cell signaling transduction in human glioma." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 563-566, (2014) (PubMed).

Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: "The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients." in: BMC cancer, Vol. 13, pp. 247, (2013) (PubMed).

Tian, Bai, Chen, Fang, Liu, Chen: "Anti-diabetic effect of methylswertianin and bellidifolin from Swertia punicea Hemsl. and its potential mechanism." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 17, Issue 7, pp. 533-9, (2010) (PubMed).

Bai, Chen, Liu, Tian, Zhou, Liu, Fang, Chen: "Effects of water extract and crude polysaccharides from Liriope spicata var. prolifera on InsR/IRS-1/PI3K pathway and glucose metabolism in mice." in: Journal of ethnopharmacology, Vol. 125, Issue 3, pp. 482-6, (2009) (PubMed).
抗原

PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

别名

PI3 kinase p85 alpha subunit (PI3K p85a 产品)

别名

PI3CG antibody, PI3K antibody, PI3Kgamma antibody, PIK3 antibody, AGM7 antibody, GRB1 antibody, p85 antibody, p85-ALPHA antibody, PI3KA antibody, AA414921 antibody, C530050K14 antibody, p50alpha antibody, p55alpha antibody, p85alpha antibody, wu:fb65b05 antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma antibody, phosphoinositide-3-kinase regulatory subunit 1 antibody, phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta antibody, phosphoinositide-3-kinase, regulatory subunit 1 (alpha) antibody, PIK3CG antibody, PIK3R1 antibody, Pik3r1 antibody, Pik3cb antibody, pik3r1 antibody

背景

Synonyms: p85, AGM7, GRB1, IMD36, p85-ALPHA, Phosphatidylinositol 3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit alpha, PI3K regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regulatory subunit p85-alpha, PIK3R1
Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

基因ID

5295

UniProt

P27986

途径

TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effect