ESR2 抗体 (AA 201-300)
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- 抗原 See all ESR2 抗体
- ESR2 (Estrogen Receptor 2 (ESR2))
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抗原表位
- AA 201-300
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适用
- 人, 小鼠, 大鼠, 绵羊
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ESR2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠, 绵羊
- 预测反应
- Cow,Pig
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human ER-beta
- 亚型
- IgG
- Top Product
- Discover our top product ESR2 Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 7, pp. 804-16, (2015) (PubMed).
: "Raloxifene upregulated mesangial cell MMP-2 activity via ER-? through transcriptional regulation." in: Cell biochemistry and biophysics, Vol. 67, Issue 2, pp. 607-13, (2013) (PubMed).
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Estrogen suppresses hepatocellular carcinoma cells through ERβ-mediated upregulation of the NLRP3 inflammasome." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 7, pp. 804-16, (2015) (PubMed).
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- 抗原
- ESR2 (Estrogen Receptor 2 (ESR2))
- 别名
- Estrogen receptor beta (ESR2 产品)
- 别名
- ER-BETA antibody, ESR-BETA antibody, ESRB antibody, ESTRB antibody, Erb antibody, NR3A2 antibody, ER[b]1 antibody, zfER-beta1 antibody, zfER[b]1 antibody, erb2 antibody, CERB antibody, ERB antibody, erb antibody, esrb antibody, estrb antibody, nr3a2 antibody, ERbeta antibody, er-beta antibody, esr-beta antibody, ESR2 antibody, ERBETA antibody, er antibody, ER-beta antibody, ER[b] antibody, Estrb antibody, ER[b]2 antibody, ER[b]a antibody, zfER[b]2 antibody, zfER-beta2 antibody, Erb2 antibody, esr2 antibody, erbeta antibody, Esr2 antibody, ERBeta2 antibody, estrogen receptor 2 antibody, estrogen receptor 2b antibody, estrogen receptor beta 2 antibody, estrogen receptor 2 (beta) antibody, estrogen receptor 2a antibody, estrogen receptor beta antibody, ESR2 antibody, esr2b antibody, erb2 antibody, esr2 antibody, Esr2 antibody, esr2a antibody, erbeta antibody
- 背景
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Synonyms: Erb, ESRB, ESTRB, NR3A2, ER-BETA, ESR-BETA, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2, ESR2
Background: Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. Isoform beta-cx lacks ligand binding ability and has no or only very low ere binding activity resulting in the loss of ligand-dependent transactivation ability. DNA-binding by ESR1 and ESR2 is rapidly lost at 37 degrees Celsius in the absence of ligand while in the presence of 17 beta-estradiol and 4-hydroxy-tamoxifen loss in DNA-binding at elevated temperature is more gradual.
- 基因ID
- 2100
- UniProt
- Q92731
- 途径
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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