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SOCS1 抗体 (AA 121-211)

Name: SOCS1 抗体 (AA 121-211)
SKU: ABIN725135
Availability: OutOfStock

SOCS1 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-Socs1Polyclonal Antibody (ABIN725135), Unconjugated at 1:300, followed by conjugation to the secondary antibody and DAB staining (SOCS1 抗体 (AA 121-211))

IHC

Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-SOCS 1 Polyclonal Antibody (ABIN725135), Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining (SOCS1 抗体 (AA 121-211))

IHC

Formalin-fixed and paraffin embedded: rat brain tissue labeled with Anti-SOCS 1 Polyclonal Antibody , Unconjugated 1:200 followed by conjugation to the secondary antibody and DAB staining (SOCS1 抗体 (AA 121-211))

IHC (p)

3 images

产品编号 ABIN725135

发货至: 中国

Datasheet as PDF

抗原 See all SOCS1 抗体

SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
抗原表位
14

13

8

7

2

2

2

1

1

1

1

1

1

1
AA 121-211
适用
67

37

31

6

5

4

3

3

3

3

2
人
宿主
64

5

2
兔
Compatible Secondaries
克隆类型
67

4
多克隆
标记
37

6

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This SOCS1 antibody is un-conjugated
应用范围
41

21

17

12

12

11

10

9

4

4

3

2

2

1
ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人

预测反应

Mouse,Rat,Cow,Pig,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Socs 1

亚型

IgG

Top Product

Discover our top product SOCS1 Primary Antibody
anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibody
SOCS1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibody
Verified SOCS1 适用: 人, 小鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibody
SOCS1 适用: 人 IHC, IF 宿主: 兔 Monoclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (N-Term) antibody
SOCS1 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, 犬, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66) antibody
SOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (C-Term) antibody
SOCS1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 35-66), (N-Term) antibody
SOCS1 适用: 小鼠, 大鼠 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB17347 unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) antibody
SOCS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 1-211) antibody
SOCS1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Suppressor of Cytokine Signaling 1 (SOCS1) (AA 21-70) antibody
SOCS1 适用: 人, 小鼠, 大鼠, Cow, Pig, 兔, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))

别名

SOCS1 (SOCS1 产品)

别名

socs1 antibody, zgc:91868 antibody, jab antibody, cis1 antibody, ssi1 antibody, tip3 antibody, cish1 antibody, ssi-1 antibody, socs-1 antibody, SOCS1 antibody, LOC100228306 antibody, socs1b antibody, CIS1 antibody, CISH1 antibody, JAB antibody, SOCS-1 antibody, SSI-1 antibody, SSI1 antibody, TIP3 antibody, Cish1 antibody, Cish7 antibody, Socs-1 antibody, suppressor of cytokine signaling 1a antibody, suppressor of cytokine signaling 1 antibody, suppressor of cytokine signaling 1 L homeolog antibody, socs1a antibody, socs1 antibody, SOCS1 antibody, socs1.L antibody, Socs1 antibody

背景

Synonyms: JAB, CIS1, SSI1, TIP3, CISH1, SSI-1, SOCS-1, Suppressor of cytokine signaling 1, JAK-binding protein, STAT-induced STAT inhibitor 1, Tec-interacting protein 3, TIP-3, SOCS1
Background: SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in negative regulation of cytokines that signal through the JAK/STAT3 pathway. Through binding to JAKs, inhibits their kinase activity. In vitro, also suppresses Tec protein-tyrosine activity. Appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF). Regulates interferon-gamma mediated sensory neuron survival (By similarity). Probable substrate recognition component of an ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Seems to recognize JAK2. SOCS1 appears to be a negative regulator in IGF1R signaling pathway.

基因ID

8651

UniProt

O15524

途径

JAK/STAT Signaling, Interferon-gamma Pathway, TLR signaling, Response to Growth Hormone Stimulus