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TGFB1 抗体 (AA 351-390)

Name: TGFB1 抗体 (AA 351-390)
SKU: ABIN724685
Availability: OutOfStock

TGFB1 适用: 人, 小鼠, 大鼠, 绵羊, 兔 WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human flat moss tinea labeled with Anti-TGF-beta-1 Polyclonal Antibody, Unconjugated (ABIN724685) 1:200 followed by conjugation to the secondary antibody and DAB staining (TGFB1 抗体 (AA 351-390))

IHC

Formalin-fixed and paraffin embedded rat renal tissue labeled with Anti-TGF-beta-1 Polyclonal Antibody, Unconjugated (ABIN724685) 1:200 followed by conjugation to the secondary antibody and DAB staining (TGFB1 抗体 (AA 351-390))

IHC

Paraformaldehyde-fixed, paraffin embedded Rat Lung Antigen retrieval by boiling in sodium citrate buffer (pH6. (TGFB1 抗体 (AA 351-390))

IHC (p)

3 images

(16 references)

产品编号 ABIN724685

发货至: 中国

Datasheet as PDF

抗原 See all TGFB1 抗体

TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
抗原表位
54

16

15

15

9

8

8

8

7

6

5

5

4

4

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 351-390
适用
168

104

53

22

19

13

12

11

8

7

5

4

4

3

3

3

1

1

1
人, 小鼠, 大鼠, 绵羊, 兔
宿主
193

42

3

1

1

1
兔
Compatible Secondaries
克隆类型
197

43
多克隆
标记
94

33

31

13

8

5

4

4

4

4

4

4

4

4

4

4

4

2

2

2

2

2

2

1
This TGFB1 antibody is un-conjugated
应用范围
175

89

68

52

51

40

36

34

28

20

17

11

5

5

3

2

2

2

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 兔, 大鼠, 绵羊

预测反应

Dog,Cow,Pig,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human TGF-Beta 1

亚型

IgG

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TGFB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibody
TGFB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 310-390) antibody
TGFB1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 30-278) antibody
TGFB1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 62-195) antibody
TGFB1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 7F6 unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) antibody
TGFB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (Middle Region) antibody
TGFB1 适用: 小鼠, 大鼠, Cow, Pig, 绵羊, 豚鼠, 犬, 马, 山羊 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibody
TGFB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (C-Term) antibody
TGFB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Transforming Growth Factor, beta 1 (TGFB1) (AA 279-390) antibody
TGFB1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Shang, Liu, Liu, Li, Dou, Zhang, Sun, Zhang, Zhu, Mu, Ding, Wen: "Telmisartan improves vascular remodeling through ameliorating prooxidant and profibrotic mechanisms in hypertension via the involvement of transforming growth factor-β1." in: Molecular medicine reports, Vol. 16, Issue 4, pp. 4537-4544, (2018) (PubMed).

Mao, Zhang, Qi, Jiang, Wu, Lu, Ainiwaer, Shang, Xu, Hao, Shou, Li, Li, Zhang, Bao, Wen: "Efficacy of radiotherapy for the treatment of cystic echinococcosis in naturally infected sheep." in: Infectious diseases of poverty, Vol. 6, Issue 1, pp. 88, (2017) (PubMed).

Shen, Wu, Wang, Zhao, Zhang, Li, Zhao: "Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis." in: International immunopharmacology, Vol. 46, pp. 16-22, (2017) (PubMed).

Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." in: Current eye research, Vol. 41, Issue 3, pp. 367-76, (2016) (PubMed).

Xue, Chen, Zhao, Zhao, Duan, Zheng: "The Overexpression of TGF-β and CCN2 in Intrauterine Adhesions Involves the NF-κB Signaling Pathway." in: PLoS ONE, Vol. 10, Issue 12, pp. e0146159, (2016) (PubMed).

Venter, Marques, Santos, Monte-Alto-Costa: "Use of platelet-rich plasma in deep second- and third-degree burns." in: Burns : journal of the International Society for Burn Injuries, Vol. 42, Issue 4, pp. 807-14, (2016) (PubMed).

Ganguly, Wen, Myer, Czech, Sahu, Steinmetz, Raman: "Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro." in: Nanoscale, Vol. 8, Issue 12, pp. 6542-54, (2016) (PubMed).

Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, (2016) (PubMed).

Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." in: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, (2016) (PubMed).

Shang, Liu, Liu, Zhang, Mu, Zhu, Liang, Zhai, Ding, Li, Wen: "Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats." in: Scientific reports, Vol. 6, pp. 39809, (2016) (PubMed).

Tang, Jiang, Zhou, Xia, Dai: "Increased adenosine levels contribute to ischemic kidney fibrosis in the unilateral ureteral obstruction model." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 737-743, (2015) (PubMed).

Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, (2015) (PubMed).

Sun, Li, Wen, Wang, Ji, Ma: "Immunological effect induced by mesenchymal stem cells in a rat liver transplantation model." in: Experimental and therapeutic medicine, Vol. 10, Issue 2, pp. 401-406, (2015) (PubMed).

Abdelmagid, Belcher, Moussa, Lababidi, Sondag, Novak, Sanyurah, Frara, Razmpour, Del Carpio-Cano, Safadi: "Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro." in: The American journal of pathology, Vol. 184, Issue 3, pp. 697-713, (2014) (PubMed).

Erbas, Yapislar, Oltulu, Yavaso?lu, Aktug, Taskiran: "Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 7, pp. 488-96, (2014) (PubMed).

Kou, Hu, Yao, Wang, Shen, Kang, Hong: "Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 3, pp. 283-9, (2013) (PubMed).
抗原

TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

别名

TGF beta 1 (TGFB1 产品)

别名

CED antibody, DPD1 antibody, LAP antibody, TGFB antibody, TGFbeta antibody, TGF-beta antibody, TGF-BETA-1 antibody, TGF-beta5 antibody, ced antibody, dpd1 antibody, lap antibody, tgf-beta antibody, tgfb antibody, tgfb5 antibody, tgfbeta antibody, TGF-beta1 antibody, TGFbeta1 antibody, Tgfb antibody, Tgfb-1 antibody, ai39657 antibody, tgfb1 antibody, wu:fb13a07 antibody, xx:ai39657 antibody, TGFB1 antibody, csd antibody, cdb1 antibody, cdg2 antibody, csd1 antibody, csd2 antibody, csd3 antibody, ebmd antibody, lcd1 antibody, bigh3 antibody, cdgg1 antibody, betaig-h3 antibody, TGFB4 antibody, transforming growth factor beta 1 antibody, transforming growth factor beta-1 antibody, transforming growth factor beta 1 L homeolog antibody, transforming growth factor, beta 1 antibody, transforming growth factor, beta 1a antibody, transforming growth factor beta induced L homeolog antibody, TGFB1 antibody, Tgfb1 antibody, tgfb1.L antibody, tgfb1a antibody, tgfbi.L antibody

背景

Synonyms: CED, DPD1, TGFB, TGFbeta, Transforming growth factor beta-1, TGF-beta-1, TGFB1
Background: Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.

分子量

12.8kDa

基因ID

7040

UniProt

P01137

途径

EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints