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HBd 抗体 (N-Term)

HBd 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 21G1-F1-B9-G9-D11 unconjugated
产品编号 ABIN7565770
发货至: 中国
  • 抗原 See all HBd 抗体
    HBd (Hemoglobin, delta (HBd))
    抗原表位
    • 6
    • 1
    • 1
    • 1
    N-Term
    适用
    • 11
    • 2
    • 2
    宿主
    • 10
    • 1
    小鼠
    克隆类型
    • 10
    • 1
    单克隆
    标记
    • 7
    • 2
    • 1
    • 1
    This HBd antibody is un-conjugated
    应用范围
    • 8
    • 6
    • 4
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    原理
    Hemoglobin beta A-2 Antibody
    交叉反应 (详细)
    This protein A purified mouse monoclonal antibody reacts specifically with human HbA-2 delta isoform.
    产品特性
    Synonyms: mouse anti-HbA-2 antibody, mouse anti-hemoglobin antibody, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, HbA-2 Antibody, Sickle Cell Disease (SCD)
    纯化方法
    Anti-HbA-2 is purified from tissue culture supernatant by protein A purification.
    过滤
    Sterile filtered
    免疫原

    Immunogen: Anti-Hemoglobin beta A-2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb delta-subunit conjugated to KLH.

    Immunogen Type: Conjugated Peptide

    克隆位点
    21G1-F1-B9-G9-D11
    亚型
    IgG1 kappa
    Top Product
    Discover our top product HBd Primary Antibody
  • 应用备注
    Application Note: Anti-Hemoglobin beta A-2 (MOUSE) antibody has been tested by ELISA and Western Blotting. This antibody is designed for use in lateral flow. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa. Western Blot Dilution: 1 μg/mL ELISA Dilution: 1:20,000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.00 mg/mL
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.
    有效期
    12 months
  • 抗原
    HBd (Hemoglobin, delta (HBd))
    别名
    HBD (HBd 产品)
    背景
    Background: HbA-2 or hemoglobin delta subunit antibodies detect the delta-specific sequence in the hemoglobin delta-subunit found in HbA-2. Functional hemoglobin (Hb) is a hetero tetramer and the dominant form of Adult Hb is composed of 2 alpha and 2 beta subunits (α2β2). Hemoglobin A-2 (HbA-2) is a normal but minor variant of hemoglobin A that consists of two alpha and two delta chains (α2δ2). Hemoglobin A-2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene, and HbA2 is also linked to neurological disorders. HbA-2 form exists in small amounts in all adult humans (1.5-3.1 % of all hemoglobin molecules) and is increased in people with Sickle-cell disease. Its normal biological role is not well understood. HbA-2 antibody does not react other forms of Hb including no cross-reaction to HbA or beta subunit. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.
    基因ID
    3045
    NCBI登录号
    NP_000510
    UniProt
    P02042
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