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Caspase 9 抗体 (AA 271-314)

Name: Caspase 9 抗体 (AA 271-314)
SKU: ABIN724175
Availability: OutOfStock

CASP9 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded rat brain labeled with Anti-Caspase-9 Polyclonal Antibody, Unconjugated (ABIN724175) 1:300 followed by conjugation to the secondary antibody and DAB staining (Caspase 9 抗体 (AA 271-314))

IHC

Heart lysates probed with Caspase-9 Polyclonal Antibody, Unconjugated at 1:300 dilution and 4˚C overnight incubation. (Caspase 9 抗体 (AA 271-314))

Paraformaldehyde-fixed, paraffin embedded Human Brain Antigen retrieval by boiling in sodium citrate buffer (pH6. (Caspase 9 抗体 (AA 271-314))

IHC (p)

3 images

(4 references)

产品编号 ABIN724175

发货至: 中国

Datasheet as PDF

抗原 See all Caspase 9 (CASP9) 抗体

Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
抗原表位
28

16

16

16

15

9

5

5

5

4

4

4

4

4

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 271-314
适用
218

131

107

19

17

16

10

1

1

1
人, 小鼠, 大鼠
宿主
212

16
兔
Compatible Secondaries
克隆类型
204

24
多克隆
标记
117

10

9

7

5

5

5

5

5

5

5

5

5

5

5

5

4

4

4

4

4

4

1
This Caspase 9 antibody is un-conjugated
应用范围
198

81

66

66

60

48

40

38

18

17

15

5

3

3

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human Caspase-9 subunit p35

亚型

IgG

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anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 11-120) antibody
CASP9 适用: 人, 小鼠, 大鼠, 小鸡, 犬, 兔 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) antibody
CASP9 适用: 人, 小鼠, 大鼠, 小鸡 WB, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-200) antibody
CASP9 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-200) antibody
CASP9 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 1-416) antibody
CASP9 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3B8-4G2 unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 331-416) antibody
CASP9 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (Cleaved-Asp353) antibody
CASP9 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (pThr125) antibody
CASP9 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) antibody
CASP9 适用: 人, 猴 WB, IP, IHC (p) 宿主: 小鼠 Monoclonal 2-22 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Gao, Liu, Li, Wu, Peng, Jing: "Hispidulin induces mitochondrial apoptosis in acute myeloid leukemia cells by targeting extracellular matrix metalloproteinase inducer." in: American journal of translational research, Vol. 8, Issue 2, pp. 1115-32, (2016) (PubMed).

Yin, Zhang, Cao, Duan, Shi, Zhao, Camara, Shen, Wang: "Bmi1 inhibition enhances the sensitivity of pancreatic cancer cells to gemcitabine." in: Oncotarget, Vol. 7, Issue 24, pp. 37192-37204, (2016) (PubMed).

Shan, Fan: "Cytotoxicity of carteolol to human corneal epithelial cells by inducing apoptosis via triggering the Bcl-2 family protein-mediated mitochondrial pro-apoptotic pathway." in: Toxicology in vitro : an international journal published in association with BIBRA, Vol. 35, pp. 36-42, (2016) (PubMed).

Pang, Fan: "Cytotoxic effect and possible mechanisms of Tetracaine on human corneal epithelial cells in vitro." in: International journal of ophthalmology, Vol. 9, Issue 4, pp. 497-504, (2016) (PubMed).
抗原

Caspase 9 (CASP9) (Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))

别名

Caspase-9 (CASP9 产品)

别名

CASP9 antibody, AI115399 antibody, APAF-3 antibody, AW493809 antibody, CASP-9 antibody, Caspase-9 antibody, ICE-LAP6 antibody, Mch6 antibody, Apaf3 antibody, Casp-9-CTD antibody, Casp9_v1 antibody, Ice-Lap6 antibody, APAF3 antibody, MCH6 antibody, PPP1R56 antibody, caspase 9 antibody, CASP9 antibody, Casp9 antibody

背景

Synonyms: MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6, Caspase-9, CASP-9, Apoptotic protease Mch-6, Apoptotic protease-activating factor 3, ICE-like apoptotic protease 6, CASP9
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.

基因ID

842

UniProt

P55211

途径

MAPK Pathway, RTK signaling, Apoptosis, Caspase Cascade in Apoptosis, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Endopeptidase Activity