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PP2A alpha/beta 抗体 (AA 205-309)

PP2A A/B 适用: 人, 小鼠 WB, IF (cc), IF (p), ELISA, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN723875
发货至: 中国
  • 抗原 See all PP2A alpha/beta (PP2A A/B) products
    PP2A alpha/beta (PP2A A/B)
    抗原表位
    • 16
    • 15
    • 1
    AA 205-309
    适用
    • 44
    • 28
    • 27
    • 9
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 40
    • 2
    • 1
    • 1
    克隆类型
    • 34
    • 10
    多克隆
    标记
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
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    • 2
    • 1
    • 1
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    This PP2A alpha/beta antibody is un-conjugated
    应用范围
    • 37
    • 26
    • 25
    • 13
    • 10
    • 6
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Pig,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human PP-2A
    亚型
    IgG
  • 应用备注
    WB 1:300-5000
    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • Lin, Bo, Tan, Sun, Song, Zhao, Ma, Li, Zheng, Xu: "Feasibility of ?-Sheet Breaker Peptide-H102 Treatment for Alzheimer's Disease Based on ?-Amyloid Hypothesis." in: PLoS ONE, Vol. 9, Issue 11, pp. e112052, (2014) (PubMed).

    Zhao, Di, Liu, Liu, Lai, Lü: "Involvement of GSK3 and PP2A in ginsenoside Rb1's attenuation of aluminum-induced tau hyperphosphorylation." in: Behavioural brain research, Vol. 241, pp. 228-34, (2013) (PubMed).

  • 抗原
    PP2A alpha/beta (PP2A A/B)
    别名
    PP2A alpha / beta (PP2A A/B 产品)
    背景

    Synonyms: RP-C, PP2Ac, PP2CA, PP2Calpha, Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform, PP2A-alpha, Replication protein C, PPP2CA

    Background: PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGOL2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). Can dephosphorylate SV4 large T antigen and p53/TP53. Activates RAF1 by dephosphorylating it at 'Ser-259'.

    基因ID
    5515
    UniProt
    P67775
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