Recombinant HbA1c 抗体 (N-Term)
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- 抗原 See all HbA1c 抗体
- HbA1c (Glycated Hemoglobin HbA1c (HbA1c))
- 抗体类型
- Recombinant Antibody
- 抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- Chimeric
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标记
- This HbA1c antibody is un-conjugated
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应用范围
- ELISA
- 原理
- Anti-HbA1c [1G8], Rabbit IgG, kappa
- 特异性
- This antibody binds human hemoglobin glycated at the N-terminal valine of the hemoglobin β chain and does not cross react with non-glycated hemoglobin. Glycated hemoglobin is formed by the conjugation of a hexose sugar to the beta-chain of hemoglobin. Glycosylated hemoglobin A1c (HbA1c) levels are used as an indicator of average plasma glucose concentration in diabetic patients. Levels of more than 48 mmol/mol (6.5 % ) are used as a criterion for the diagnosis of diabetes. Higher levels of HbA1c are also associated with cardiovascular disease.
- 产品特性
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
- 纯化方法
- Protein A affinity purified
- 免疫原
- The original antibody was generated by immunizing BALB/c mice with synthetic N-terminal glycopeptide (VHLTPEC) and KLH conjugate.
- 克隆位点
- 1G8
- 亚型
- IgG kappa
- Top Product
- Discover our top product HbA1c Primary Antibody
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- 应用备注
- This antibody is recommended for detection of HbA1c levels in plasma and blood samples. The binding reactivity of this antibody towards HbA1c and non-glycated hemoglobin was done using indirect ELISA. The binding reactivity of this antibody to HbA1c was compared to commercially available anti-HbA1c antibody BM300-F7C2 and it was reported that this antibody showed better specificity for HbA1c (CN110724671).
- 说明
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This is a chimeric antibody made using the variable domain sequences of the original Mouse IgG2a to improve compatibility with existing reagents, assays, and techniques.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % Proclin 300.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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