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Recombinant SIRPG 抗体

SIRPG 适用: 人 ELISA, FACS, IP, BR 宿主: 小鼠 Monoclonal OX-119 unconjugated Recombinant Antibody
产品编号 ABIN7543054
发货至: 中国
  • 抗原 See all SIRPG 抗体
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    抗体类型
    Recombinant Antibody
    适用
    • 45
    • 7
    • 7
    • 3
    • 3
    • 1
    宿主
    • 30
    • 15
    小鼠
    克隆类型
    • 30
    • 14
    • 1
    单克隆
    标记
    • 25
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIRPG antibody is un-conjugated
    应用范围
    • 24
    • 17
    • 14
    • 9
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Blocking Reagent (BR)
    原理
    Anti-SIRP g [OX-119], Mouse IgG1, kappa
    特异性
    Hybridoma supernatants were initially screened by ELISA, using SIRPg-CD4, human SIRPa-Fc, human SIRPb-Fc or CD4 to eliminate hybridomas with cross-reactivity to rat CD4, human SIRPa, and SIRPb. There is some marginal binding of OX-119 to SIRPb transfected 293T cells. SIRPg binds CD47. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. Expressed on CD4+ T-cells, CD8+ T-cells, CD56-bright natural killer (NK) cells, CD20+ cells, and all activated NK cells..
    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法
    Protein A affinity purified
    免疫原
    OX-119 was prepared by immunizing BALB/c mice with a chimeric protein made up of human SIRPg and a leader peptide of rat CD4 domain (SIRPg-CD4 ).
    克隆位点
    OX-119
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SIRPG Primary Antibody
  • 应用备注
    OX-119 is able to perform staining of peripheral blood myeloid cells (PBMCs) and block SIRPg-mediated apoptosis. OX-119 can also be used in IP, FC and ELISA.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    SIRPG (Signal-Regulatory Protein gamma (SIRPG))
    别名
    SIRP g (SIRPG 产品)
    背景
    CD172g, OX119, MRC OX-119, MRC OX119, SIRP-g, SIRPg, SIRP gamma, SIRP-gamma, CD172 antigen-like family member B, signal-regulatory protein beta, CD172-g
    UniProt
    Q9P1W8
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