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Recombinant CD45RC 抗体

CD45RC 适用: 大鼠 FACS, IP, IHC 宿主: 兔 Chimeric OX-22 unconjugated Recombinant Antibody
产品编号 ABIN7543009
发货至: 中国
  • 抗原 See all CD45RC 抗体
    CD45RC
    抗体类型
    Recombinant Antibody
    适用
    • 19
    • 9
    • 3
    • 2
    大鼠
    宿主
    • 19
    • 14
    克隆类型
    • 33
    Chimeric
    标记
    • 15
    • 6
    • 6
    • 6
    This CD45RC antibody is un-conjugated
    应用范围
    • 32
    • 9
    • 6
    • 5
    • 4
    • 2
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC)
    原理
    Anti-CD45RC [OX-22], Rabbit IgG, kappa
    特异性
    OX-22 binds specifically to the high molecular weight form of the leucocyte common antigen, CD45RC. OX-22 and OX-31 compete for binding but do not compete with OX-32. The antigen is expresssed on the surface of B cells, around half of bone marrow cells, all CD8+ve T cells, and is able to differentiate between CD4+CD45RChigh (Th1-like) and CD4+CD45RClow (Th2-like) cell types. CD45 extracellular domain is able to interact with a number of different proteins including CD4, TCR, CD2, Thy-1 and CD26. CD45 is important for signalling throguh the T cell receptor and in the selection of T and B lymphocytes.
    产品特性

    Original Species of Ab: Mouse

    Original Format of Ab: IgG1

    纯化方法
    Protein A affinity purified
    免疫原
    OX-22 was prepared by immunizing BALB/c mice with phytohemagglutinin-activated rat lymph node cells.
    克隆位点
    OX-22
    亚型
    IgG kappa
    Top Product
    Discover our top product CD45RC Primary Antibody
  • 应用备注
    OX-20 can be used for both FC and IHC (paraffin/frozen) studies. It can also be used to purify proteins by affinty-purification (Woolett et al. Eur J Immunol. 1985 Feb,15(2):168-73).
    说明

    This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % Proclin 300.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
  • 抗原
    CD45RC
    别名
    CD45RC (CD45RC 产品)
    背景
    L-CA, Receptor-type tyrosine-protein phosphatase C, leukocyte common antigen, T200, CD45, OX22, MRC OX22, MRC OX-22, CD45 R
    UniProt
    P04157
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