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CD207 抗体 (PE)

CD207 适用: 人 FACS 宿主: 小鼠 Monoclonal 2G3 PE
产品编号 ABIN7540425
发货至: 中国
  • 抗原 See all CD207 抗体
    CD207 (CD207 Molecule, Langerin (CD207))
    适用
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    宿主
    • 45
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    小鼠
    克隆类型
    • 45
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    单克隆
    标记
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    This CD207 antibody is conjugated to PE
    应用范围
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    Flow Cytometry (FACS)
    原理
    Anti-Hu CD207 PE
    特异性
    The mouse monoclonal antibody 2G3 recognizes an extracellular/luminal epitope of CD207, a transmembrane protein selectively expressed by Langerhans cells and by some other dendritic cell subsets. This antibody clone can target vaccine-peptides to dendritic cells.
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Fusion protein of human CD207 extracellular part and IgG Fc fragment
    克隆位点
    2G3
    亚型
    IgG1 lambda
    Top Product
    Discover our top product CD207 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    CD207 (CD207 Molecule, Langerin (CD207))
    别名
    CD207 (CD207 产品)
    背景

    NCBI Full Gene Name: CD207 Molecule

    Description: CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.

    Other names: CLEC4K, langerin

    Gene name: CD207

    基因ID
    50489
    UniProt
    Q9UJ71
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