DCLK2 抗体 (AA 652-766)
-
- 抗原 See all DCLK2 抗体
- DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
-
抗原表位
- AA 652-766
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This DCLK2 antibody is un-conjugated
-
应用范围
- ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- DCLK2 Antibody
- 纯化方法
- Purified antibody
- 免疫原
- Purified recombinant fragment of human DCLK2 (AA: 652-766) expressed in mammalian.
- 克隆位点
- 3H1G4
- 亚型
- IgG2a
- Top Product
- Discover our top product DCLK2 Primary Antibody
-
-
- 应用备注
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- 限制
- 仅限研究用
-
- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
- 抗原
- DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))
- 别名
- DCLK2 (DCLK2 产品)
- 背景
-
Description: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.
Aliases: CL2, DCK2, CLIK2, DCDC3, CLICK2, DCDC3B, DCAMKL2, CLICK-II
- 分子量
- 83.6 kDa
- 基因ID
- 166614
- UniProt
- Q8N568
-