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FcRn 抗体

FcRn 适用: 人 ELISA, IF, FACS, cELISA, Func 宿主: 小鼠 Monoclonal ADM31 unconjugated
产品编号 ABIN7539617
发货至: 中国
  • 抗原 See all FcRn 抗体
    FcRn (IgG receptor FcRn (FcRn))
    适用
    • 42
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 39
    • 8
    • 1
    小鼠
    克隆类型
    • 40
    • 8
    单克隆
    标记
    • 23
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
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    This FcRn antibody is un-conjugated
    应用范围
    • 30
    • 27
    • 8
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Cell-ELISA (cELISA), Functional Studies (Func)
    产品特性
    based on recognition of the complete native protein expressed on transfected mammalian cells
    纯化方法
    Purified, Protein G
    免疫原
    hFcRn
    克隆位点
    ADM31
    亚型
    IgG2b lambda
    Top Product
    Discover our top product FcRn Primary Antibody
  • 应用备注
    • Flow cytometry: 1.2 μg/10^6 cells
    • ELISA: 1:200 - 1:400
    • CELISA: 1:200 - 1:400
    For each application a titration should be performed to determine the optimal concentration.
    限制
    仅限研究用
  • 缓冲液
    PBS pH 7.2 with 50% glycerol
    注意事项
    avoid repeated freezing and thawing
    储存条件
    4 °C
  • 抗原
    FcRn (IgG receptor FcRn (FcRn))
    别名
    Fc Receptor (FcRn) FcRn (FcRn 产品)
    别名
    FCRN antibody, alpha-chain antibody, FcRn antibody, Fc fragment of IgG receptor and transporter antibody, Fc receptor, IgG, alpha chain transporter antibody, FCGRT antibody, Fcgrt antibody
    背景
    The MHC class I-like Fc receptor (FcRn) is an intracellular trafficking Fc receptor that is uniquely responsible for the extended serum half-life of antibodies of the IgG subclass and their ability to transport across cellular barriers. By performing these functions, FcRn affects numerous facets of antibody biology and pathobiology. Its critical role in controlling IgG pharmacokinetics has been leveraged for the design of therapeutic antibodies and related biologics. FcRn also traffics serum albumin and is responsible for the enhanced pharmacokinetic properties of albumin-conjugated therapeutics.
    Synonyms: IgG receptor FcRn large subunit p51, Neonatal Fc receptor, FCGRT
    UniProt
    P55899
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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