EPH Receptor A7 抗体 (AA 181-280)
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- 抗原 See all EPH Receptor A7 (EPHA7) 抗体
- EPH Receptor A7 (EPHA7)
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抗原表位
- AA 181-280
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPH Receptor A7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- There is a chance that this protein will cross-react with EphA4 based on a 73 % non-sequential sequence similarity.
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human EphA7
- 亚型
- IgG
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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- 抗原
- EPH Receptor A7 (EPHA7)
- 别名
- EphA7 (EPHA7 产品)
- 别名
- fc51g03 antibody, wu:fc51g03 antibody, si:dkey-23k6.1 antibody, EHK3 antibody, HEK11 antibody, Cek11 antibody, Ebk antibody, Ehk3 antibody, Hek11 antibody, Mdk1 antibody, CEPHA7 antibody, EPH receptor A7 antibody, eph receptor A7 antibody, ephrin type-B receptor 1-B antibody, Eph receptor A7 antibody, EPHA7 antibody, epha7 antibody, LOC100166161 antibody, Epha7 antibody
- 背景
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Synonyms: EHK3, EK11, EHK-3, HEK11, Ephrin type-A receptor 7, EPH homology kinase 3, EPH-like kinase 11, EPHA7
Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus. May also regulate brain development through a caspase(CASP3)-dependent proapoptotic activity. Forward signaling may result in activation of components of the ERK signaling pathway including MAP2K1, MAP2K2, MAPK1 AND MAPK3 which are phosphorylated upon activation of EPHA7.
- 基因ID
- 2045
- UniProt
- Q15375
- 途径
- RTK signaling
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