Amphiregulin 抗体
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- 抗原 See all Amphiregulin (AREG) 抗体
- Amphiregulin (AREG)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Amphiregulin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 原理
- Amphiregulin antibody
- 纯化方法
- Protein A purified
- 免疫原
- recombinant human Amphiregulin
- Top Product
- Discover our top product AREG Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- 缓冲液
- PBS
- 储存条件
- 4 °C,-20 °C
- 储存方法
- The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
- 有效期
- 24 months
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- 抗原
- Amphiregulin (AREG)
- 别名
- Amphiregulin (AREG 产品)
- 别名
- AR antibody, CRDGF antibody, SDGF antibody, Sdgf antibody, AREG antibody, AREGB antibody, AREG/SDGF antibody, amphiregulin antibody, AREG antibody, Areg antibody
- 背景
- AREG, AR, SDGF, AREGB, CRDGF,Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.
- 基因ID
- 374
- NCBI登录号
- NM_001657, NP_001648
- UniProt
- P15514
- 途径
- RTK signaling, EGFR Signaling Pathway
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