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Amphiregulin 抗体

AREG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7539230
发货至: 中国
  • 抗原 See all Amphiregulin (AREG) 抗体
    Amphiregulin (AREG)
    适用
    • 32
    • 11
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    • 1
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    宿主
    • 27
    • 9
    • 1
    • 1
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    克隆类型
    • 31
    • 8
    多克隆
    标记
    • 27
    • 3
    • 2
    • 1
    • 1
    • 1
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    This Amphiregulin antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 11
    • 7
    • 6
    • 3
    • 3
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    • 1
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    Western Blotting (WB), Immunofluorescence (IF)
    原理
    Amphiregulin antibody
    纯化方法
    Protein A purified
    免疫原
    recombinant human Amphiregulin
    Top Product
    Discover our top product AREG Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS
    储存条件
    4 °C,-20 °C
    储存方法
    The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.
    有效期
    24 months
  • 抗原
    Amphiregulin (AREG)
    别名
    Amphiregulin (AREG 产品)
    别名
    AR antibody, CRDGF antibody, SDGF antibody, Sdgf antibody, AREG antibody, AREGB antibody, AREG/SDGF antibody, amphiregulin antibody, AREG antibody, Areg antibody
    背景
    AREG, AR, SDGF, AREGB, CRDGF,Amphiregulin is an EGF related growth factor that signals through the EGF/TGF-a receptor, and stimulates growth of keratinocytes, epithelial cells and some fibroblasts. Amphiregulin also inhibits the growth of certain carcinoma cell lines. Synthesized as a transmembrane protein, Amphiregulin's extracellular domain is proteolytically processed to release the mature protein. There are 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds essential for biological activity. Recombinant human Amphiregulin is a 11.3 kDa glycoprotein consisting of 98 amino acid residues.
    基因ID
    374
    NCBI登录号
    NM_001657, NP_001648
    UniProt
    P15514
    途径
    RTK signaling, EGFR Signaling Pathway
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