GLMN 抗体 (AA 151-250) (Biotin)
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- 抗原 See all GLMN 抗体
- GLMN (Glomulin, FKBP Associated Protein (GLMN))
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抗原表位
- AA 151-250
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GLMN antibody is conjugated to Biotin
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 预测反应
- Mouse,Rat,Dog,Pig,Horse
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human FK506 binding protein associated protein
- 亚型
- IgG
- Top Product
- Discover our top product GLMN Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- GLMN (Glomulin, FKBP Associated Protein (GLMN))
- 别名
- FK506 binding protein associated protein (GLMN 产品)
- 别名
- FAP antibody, FAP48 antibody, FAP68 antibody, FKBPAP antibody, GLML antibody, GVM antibody, VMGLOM antibody, 9330160J16Rik antibody, AW227515 antibody, Fap48 antibody, Fap68 antibody, MGC69174 antibody, GLMN antibody, zgc:194957 antibody, glmnl antibody, zgc:101567 antibody, glomulin, FKBP associated protein antibody, glomulin, FKBP associated protein L homeolog antibody, glomulin, FKBP associated protein b antibody, glomulin, FKBP associated protein a antibody, GLMN antibody, Glmn antibody, glmn.L antibody, glmn antibody, glmnb antibody, glmna antibody
- 背景
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Synonyms: FAP, GVM, GLML, FAP48, FAP68, FKBPAP, VMGLOM, Glomulin, FK506-binding protein-associated protein, FKBP-associated protein, GLMN, GLMN_HUMAN
Background: Isoform 1: Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes.). Inhibits E3 ubiquitin ligase activity by binding to RBX1 (via RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1. Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels (By similarity). Essential for normal development of the vasculature. Contributes to the regulation of RPS6KB1 phosphorylation
- 基因ID
- 11146
- UniProt
- Q92990
- 途径
- Tube Formation
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