Recombinant 4-1BB (Utomilumab Biosimilar) 抗体
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- 抗原 See all 4-1BB (Utomilumab Biosimilar) products
- 4-1BB (Utomilumab Biosimilar)
- 抗体类型
- Recombinant Antibody
- 适用
- 人
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宿主
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Human
- Expression System
- Mammalian cells
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克隆类型
- 单克隆
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标记
- This 4-1BB (Utomilumab Biosimilar) antibody is un-conjugated
- 应用范围
- ELISA, Western Blotting (WB)
- 原理
- Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade
- 产品特性
- Antibody Type: IgG2 kappa
- 纯化方法
- Recombinant antibody expressed in mammalien cells and purified.
- 纯度
- > 85%
- 质量等级
- Research Grade
- 亚型
- IgG2
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- 限制
- 仅限研究用
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- 缓冲液
- PBS pH 7.5
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 4°C for short term, -20°C for long term
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- 抗原
- 4-1BB (Utomilumab Biosimilar)
- Abstract
- 4-1BB (Utomilumab Biosimilar) 产品
- 背景
- Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.
- CAS-编号
- 1417318-27-4
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