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Recombinant 4-1BB (Utomilumab Biosimilar) 抗体

Research Grade 适用: 人 ELISA, WB 宿主: Human Monoclonal unconjugated Recombinant Antibody
产品编号 ABIN7538049
发货至: 中国
  • 抗原 See all 4-1BB (Utomilumab Biosimilar) products
    4-1BB (Utomilumab Biosimilar)
    抗体类型
    Recombinant Antibody
    适用
    宿主
    • 1
    Human
    Expression System
    Mammalian cells
    克隆类型
    • 1
    单克隆
    标记
    • 1
    This 4-1BB (Utomilumab Biosimilar) antibody is un-conjugated
    应用范围
    ELISA, Western Blotting (WB)
    原理
    Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade
    产品特性
    Antibody Type: IgG2 kappa
    纯化方法
    Recombinant antibody expressed in mammalien cells and purified.
    纯度
    > 85%
    质量等级
    Research Grade
    亚型
    IgG2
  • 限制
    仅限研究用
  • 缓冲液
    PBS pH 7.5
    储存条件
    4 °C,-20 °C
    储存方法
    4°C for short term, -20°C for long term
  • 抗原
    4-1BB (Utomilumab Biosimilar)
    Abstract
    4-1BB (Utomilumab Biosimilar) 产品
    背景
    Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.
    CAS-编号
    1417318-27-4
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