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PPM1D 抗体

PPM1D 适用: 人, 小鼠 WB, ELISA, IHC (p), ICC 宿主: 小鼠 Monoclonal 7E11-C5 unconjugated
产品编号 ABIN7506213
发货至: 中国
  • 抗原 See all PPM1D 抗体
    PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
    适用
    • 54
    • 12
    • 11
    • 1
    人, 小鼠
    宿主
    • 52
    • 2
    小鼠
    克隆类型
    • 52
    • 2
    单克隆
    标记
    • 18
    • 5
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    • 1
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    • 1
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    This PPM1D antibody is un-conjugated
    应用范围
    • 43
    • 26
    • 13
    • 8
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    原理
    Anti-PPM1D Purified
    特异性
    The mouse monoclonal antibody 7E11/C5 recognizes an epitope within the sequence FTNEDELYNLLTDSP of PPM1D, a protein phosphatase, which contributes to development of some carcinomas.
    纯化方法
    Purified by protein-A affinity chromatography.
    免疫原
    Purified human PPM1D
    克隆位点
    7E11-C5
    亚型
    IgG1
    Top Product
    Discover our top product PPM1D Primary Antibody
  • 应用备注
    Western blotting: Recommended dilution: 1-2 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    PPM1D (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1D (PPM1D))
    别名
    PPM1D (PPM1D 产品)
    别名
    PP2C-DELTA antibody, WIP1 antibody, AV338790 antibody, Wip1 antibody, zgc:103518 antibody, ppm1d antibody, wu:fj44c08 antibody, zgc:55836 antibody, zgc:77316 antibody, protein phosphatase, Mg2+/Mn2+ dependent 1D antibody, protein phosphatase 1D magnesium-dependent, delta isoform antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1D antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Db antibody, protein phosphatase, Mg2+/Mn2+ dependent 1D L homeolog antibody, protein phosphatase, Mg2+/Mn2+ dependent, 1Da antibody, PPM1D antibody, Ppm1d antibody, ppm1db antibody, ppm1d.L antibody, ppm1da antibody
    背景
    Protein phosphatase, Mg2+/Mn2+ dependent 1D,PPM1D is a Mg2+/Mn2+ dependent protein phosphatase 1D with inducible expression in response to various types of environmental stress. This expression is p53-dependent, and subsequently PPM1D negatively regulates the p53-mediated transcription, thus it suppresses the apoptosis. PPM1D contributes to development of carcinomas, and seems to be a promissing therapeutic target. Amplification of PPM1D is associated with breast cancer.,WIP1, Protein phosphatase 1D, JDVS, WIP1, IDDGIP
    基因ID
    8493
    UniProt
    O15297
    途径
    p53 Pathway, Cell Division Cycle
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