The mouse monoclonal antibody VIM15 recognizes an extracellular epitope of CD92, a 70 kDa transmembrane glycoprotein expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines.
CD92 antibody, CDW92 antibody, CHTL1 antibody, CTL1 antibody, RP11-287A8.1 antibody, Cdw92 antibody, Ctl1 antibody, 2210409B22Rik antibody, 4833416H08Rik antibody, AW547365 antibody, SLC44A1 antibody, slc44a1 antibody, zgc:112201 antibody, ctl1 antibody, solute carrier family 44 member 1 antibody, solute carrier family 44, member 1 antibody, solute carrier family 44 (choline transporter), member 1a antibody, solute carrier family 44 (choline transporter), member 1 antibody, choline transporter-like protein 1 antibody, Choline transporter-like protein 1 antibody, solute carrier family 44 (choline transporter), member 1 L homeolog antibody, SLC44A1 antibody, Slc44a1 antibody, slc44a1a antibody, slc44a1 antibody, LOC100404101 antibody, chtl-1 antibody, slc44a1.L antibody
背景
Solute carrier family 44 member 1,CD92 is a 70 kDa protein with ten transmembrane domains, intracellular N and C teminus, and two glycosylated larger extracellular loops. In the C-terminal domain, there is an ITIM-like sequence. This protein seems to be a choline transporter responsible for delivery of choline into the immune cells, to make it accessible for phospholipid synthesis, as well as a regulator of immune cell signaling. It is expressed mainly on human peripheral blood monocytes and neutrophils, and several myeloid and T-cell lines. It can also be found on mast cells (but not eosinophils), and weakly on peripheral blood lymphocytes, fibroblasts, epithelial cells, and endothelial cells.,CTL1, CHTL1, SLC44A1