Interleukin 17a 抗体
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- 抗原 See all Interleukin 17a (IL17A) 抗体
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Interleukin 17a antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- 原理
- Anti-Hu IL-17A Purified
- 特异性
- The mouse monoclonal antibody 9F9 recognizes human interleukin 17A (IL-17A, secreted or intracellular).
- 纯化方法
- Purified by protein-A affinity chromatography.
- 免疫原
- mammalian-derived human IL-17-IgG fusion protein, boost with recombinant human IL-17A
- 克隆位点
- 9F9
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product IL17A Primary Antibody
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anti-Interleukin 17A (IL17A) (AA 1-75) antibody
IL17A 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4K5F6 unconjugated
anti-Interleukin 17A (IL17A) (Internal Region) antibodyIL17A 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人 ELISA, WB, Neut 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 大鼠 ELISA, WB, IHC, Neut, RIA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) (AA 24-133) antibodyIL17A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Interleukin 17A (IL17A) antibody (FITC)IL17A 适用: 人 FACS 宿主: 小鼠 Monoclonal 9F9 FITC
anti-Interleukin 17A (IL17A) antibody (APC)IL17A 适用: 人 FACS 宿主: 小鼠 Monoclonal 9F9 APC
anti-Interleukin 17A (IL17A) antibody (PE)IL17A 适用: 人 FACS 宿主: 小鼠 Monoclonal 9F9 PE
anti-Interleukin 17A (IL17A) (AA 24-155) antibodyIL17A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: Recommended dilution: 0.5-4 μg/mL. Intracellular staining.
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Do not freeze.
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- 抗原
- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
- 别名
- IL-17A (IL17A 产品)
- 别名
- CTLA8 antibody, IL-17 antibody, IL-17A antibody, IL17 antibody, Ctla-8 antibody, Ctla8 antibody, Il17 antibody, ChIL-17 antibody, IL-17F antibody, IL17A antibody, CTLA-8 antibody, interleukin 17A antibody, IL17A antibody, Il17a antibody
- 背景
- Interleukin 17A,Interleukin 17A (IL-17A) is a proinflammatory cytokine produced by activated T cells. IL-17A-mediated downstream pathways induce the production of inflammatory molecules, chemokines, antimicrobial peptides, and remodeling proteins. It plays an important role in connecting T cell-mediated adaptive immunity and acute inflammatory response to destroy extracellular bacteria and fungi. It is the signature effector cytokine of Th17 cells, and in this role it primarily induces neutrophil activation and recruitment at infection and inflammatory sites. High levels of IL-17A are associated with rheumatoid arthritis, psoriasis, multiple sclerosis, and another inflammatory diseases, including lung injugy during severe COVID 19. This cytokine also contributes to germinal center formation by regulating the chemotactic response of B cells to CXCL12 and CXCL13, enhancing retention of B cells within the germinal centers, B cell somatic hypermutation rate and selection toward plasma cells. It is an effector cytokine for invariant NKT cells (iNKT), and it is involved in epithelial barrier formation upon injury.,Interleukin 17
- 基因ID
- 3605
- UniProt
- Q16552
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