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IgE 抗体 (PE)

适用: 人 FACS 宿主: 小鼠 Monoclonal 4H10 PE
产品编号 ABIN7505984
发货至: 中国
  • 抗原 See all IgE 抗体
    IgE
    适用
    • 20
    • 2
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    • 1
    宿主
    • 12
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    • 1
    • 1
    小鼠
    克隆类型
    • 14
    • 10
    • 1
    单克隆
    标记
    • 16
    • 4
    • 2
    • 1
    • 1
    • 1
    This IgE antibody is conjugated to PE
    应用范围
    • 12
    • 12
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
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    • 1
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    Flow Cytometry (FACS)
    原理
    Anti-Hu IgE PE
    特异性
    The mouse monoclonal antibody 4H10 reacts with human IgE, it recognizes an epitope different from the ones recognized by BE5 and 4G7 antibodies to IgE. The epitope is located within the amino acids 267-279 (TWLEDGQVMDVDL).
    纯化方法
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Purified human IgE.
    克隆位点
    4H10
    亚型
    IgG1
    Top Product
    Discover our top product IgE Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 1-5 μg/mL.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    IgE
    Abstract
    IgE 产品
    别名
    IGH2 antibody, IgE antibody, Gm900 antibody, immunoglobulin heavy chain (epsilon polypeptide) antibody, immunoglobulin heavy constant epsilon antibody, Immunoglobulin heavy constant epsilon antibody, Ighe antibody, IGHE antibody
    背景
    Immunoglobulin E (IgE) is a 180 kDa soluble protein serving as an antigen-specific unit of mast cell effector mechanisms. IgE has the lowest serum concentration of all immunoglobulins (approximately 0.5 mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically. Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor. Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.,Immunoglobulin E
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