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GZMA 抗体

GZMA 适用: 人 IP, FACS, ICC 宿主: 小鼠 Monoclonal CB9 unconjugated
产品编号 ABIN7505978
发货至: 中国
  • 抗原 See all GZMA 抗体
    GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
    适用
    • 45
    • 28
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    • 1
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    宿主
    • 44
    • 7
    • 3
    小鼠
    克隆类型
    • 47
    • 7
    单克隆
    标记
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    This GZMA antibody is un-conjugated
    应用范围
    • 33
    • 18
    • 13
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
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    Immunoprecipitation (IP), Flow Cytometry (FACS), Immunocytochemistry (ICC)
    原理
    Anti-Hu Granzyme A Purified
    特异性
    The mouse monoclonal CB9 recognizes granzyme A, a 28 kDa serine protease expressed intracellularly in activated Tc cells and NK cells.
    纯化方法
    Purified by protein-A affinity chromatography.
    免疫原
    Full length human granzyme A
    克隆位点
    CB9
    亚型
    IgG1 kappa
    Top Product
    Discover our top product GZMA Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 5-10 μg/mL, intracellular staining.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    GZMA (Granzyme A (Granzyme 1, Cytotoxic T-Lymphocyte-Associated serine Esterase 3) (GZMA))
    别名
    Granzyme A (GZMA 产品)
    别名
    gzmA antibody, GZMA antibody, AW494114 antibody, Ctla-3 antibody, Ctla3 antibody, Hf antibody, SE1 antibody, TSP-1 antibody, TSP1 antibody, CTLA3 antibody, HFSP antibody, granzyme A antibody, Granzyme A antibody, granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) antibody, gzmA antibody, GZMA antibody, graa antibody, Gzma antibody
    背景
    Granzyme A,Granzyme A is a serine protease expressed in the cytoplasmic granules of T cells and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Similarly to granzyme B, granzyme A acts to destroy the target cells by proteolysis of their particular components. In case of granzyme A the targets are e.g. APEX1 (it destroys its oxidative repair activity), and nucleosome assembly protein SET (it disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA).,HFSP, CTLA3, GrA
    基因ID
    3001
    UniProt
    P12544
    途径
    Apoptosis
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