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C5AR1 抗体 (AA 15-27) (APC)

C5AR1 适用: 人, Cow, 兔, 雪貂 FACS 宿主: 小鼠 Monoclonal S5-1 APC
产品编号 ABIN7505962
发货至: 中国
  • 抗原 See all C5AR1 抗体
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    抗原表位
    • 15
    • 13
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 15-27
    适用
    • 104
    • 19
    • 18
    • 13
    • 11
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, Cow, 兔, 雪貂
    宿主
    • 77
    • 25
    • 17
    • 1
    • 1
    小鼠
    克隆类型
    • 79
    • 37
    • 2
    单克隆
    标记
    • 58
    • 11
    • 10
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C5AR1 antibody is conjugated to APC
    应用范围
    • 68
    • 56
    • 37
    • 19
    • 15
    • 13
    • 13
    • 12
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    原理
    Anti-Hu CD88 APC
    特异性
    The mouse monoclonal antibody S5/1 recognizes an extracellular epitope of CD88 protein, a 43 kDa receptor of C5a component of the complement cascade.
    纯化方法
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    免疫原
    Recombinant N-terminal peptide (Asp15-Asp27) of human C5aR
    克隆位点
    S5-1
    亚型
    IgG2a kappa
    Top Product
    Discover our top product C5AR1 Primary Antibody
  • 应用备注
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    限制
    仅限研究用
  • 缓冲液
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原
    C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
    别名
    CD88 (C5AR1 产品)
    别名
    C5A antibody, C5AR antibody, C5R1 antibody, CD88 antibody, C5aR antibody, C5r1 antibody, Cd88 antibody, D7Msu1 antibody, GPR77 antibody, complement C5a receptor 1 antibody, complement component 5a receptor 1 antibody, C5AR1 antibody, C5ar1 antibody, c5ar1 antibody
    背景
    Complement C5a receptor 1,CD88 / C5aR is a G protein-coupled seven membrane-spanning protein serving as a receptor for C5a component of the complement cascade, and is expressed mainly by monocytes, macrophages, neutrophils, eosinophils, and mast cells, but also e.g. by hepatocytes, glial cells, vascular endothelial cells, or cardiomyocytes. The binding of C5a to CD88 is associated with inflammatory response, including superoxide anion production, chemotaxis, and increased production of acute phase proteins. Expression of CD88 on synovial mast cells and their C5a-mediated degranulation plays a role in pathogenesis of rheumatoid arthritis.,C5A, C5R1, C5AR1
    基因ID
    728
    UniProt
    P21730
    途径
    Complement System
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