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- 抗原 See all CD51/CD61 (ITGAV/ITGB3) 抗体
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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适用
- 人, 小鸡
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD51/CD61 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 原理
- Anti-Hu CD51/CD61 PE
- 特异性
- The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
- 无交叉反应
- Cow, Pig, 兔
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- A cell suspension containing osteoclasts from osteoclastomas
- 克隆位点
- 23C6
- 亚型
- IgG1
- Top Product
- Discover our top product ITGAV/ITGB3 Primary Antibody
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anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody
ITGAV/ITGB3 适用: 人, 小鼠, 大鼠 FACS, WB, IF (cc), IF (p), IHC (fro), ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibody (FITC)ITGAV/ITGB3 适用: 人 FACS, IHC 宿主: 小鼠 Monoclonal BV3 FITC
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡, 兔 FACS, IHC, IHC (fro) 宿主: 小鼠 Monoclonal 23C6 unconjugated
anti-Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3) antibodyITGAV/ITGB3 适用: 人, 小鸡 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal 23C6 unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- 别名
- CD51/CD61 (ITGAV/ITGB3 产品)
- 别名
- CD51 antibody, MSK8 antibody, VNRA antibody, VTNR antibody, integrin subunit alpha V antibody, ITGAV antibody
- 背景
- CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR
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