Integrin alpha 1 抗体 (PE)
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- 抗原 See all Integrin alpha 1 (ITGA1) 抗体
- Integrin alpha 1 (ITGA1)
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适用
- 人, Non-Human Primate
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Integrin alpha 1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 原理
- Anti-Hu CD49a PE
- 特异性
- The mouse monoclonal antibody TS2/7 recognizes an extracellular epitope of CD49a, the alpha 1 chain of VLA integrin complex, that serves as an adhesion receptor for collagen IV and laminin 1.
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- human CTL line
- 克隆位点
- TS2-7
- 亚型
- IgG1
- Top Product
- Discover our top product ITGA1 Primary Antibody
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- Integrin alpha 1 (ITGA1)
- 别名
- CD49a (ITGA1 产品)
- 别名
- CD49A antibody, E130012M19Rik antibody, Vla1 antibody, CD49a antibody, VLA1 antibody, integrin alpha 1 antibody, integrin subunit alpha 1 antibody, Itga1 antibody, ITGA1 antibody
- 背景
- Integrin subunit alpha 1,CD49a is the alpha 1 chain of VLA integrin complex (together with CD29, serving as the beta 1 chain), and is expressed on activated T cells, monocytes, NK cells, cultured neuronal cells, melanoma cells, mesenchymal cells (including smooth muscle cells), fibroblasts, hepatocytes, and microvascular endothelium. It binds to collagen IV and laminin 1. It is important for leukocyte migration into tissues. It is upregulated in inflammatory tissues, such as inflammed intestine.,alpha 1 integrin, VLA-1 alpha, ITGA1
- 基因ID
- 3672
- UniProt
- P56199
- 途径
- EGFR Signaling Pathway, CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor, Integrin Complex
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