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- 抗原 See all TREM1 抗体
- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TREM1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 原理
- Anti-Hu CD354 PE
- 特异性
- The mouse monoclonal antibody 6B1 (also known as 6B1.1G12) recognizes an extracellular epitope of human CD354 (TREM-1), a transmembrane glycoprotein, serving as an important innate immunity receptor.
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- recombinant human CD354 fused with IgG
- 克隆位点
- 6B1
- 亚型
- IgG1
- Top Product
- Discover our top product TREM1 Primary Antibody
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anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibody
TREM1 适用: 人, 大鼠, 猴 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 6B12D1 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibodyTREM1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-205) antibodyTREM1 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 5F9F7 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-230) antibodyTREM1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-234) antibodyTREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 74-90) antibodyTREM1 适用: 小鼠 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-234) antibodyTREM1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibodyTREM1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal TREM-37 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) antibodyTREM1 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 6B1 unconjugated
anti-Triggering Receptor Expressed On Myeloid Cells 1 (TREM1) (AA 21-130) antibodyTREM1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- 抗原
- TREM1 (Triggering Receptor Expressed On Myeloid Cells 1 (TREM1))
- 别名
- CD354 (TREM1 产品)
- 别名
- TREM1 antibody, CD354 antibody, TREM-1 antibody, triggering receptor expressed on myeloid cells 1 antibody, TREM1 antibody, Trem1 antibody, LOC100349504 antibody
- 背景
- Triggering receptor expressed on myeloid cells 1,CD354 (TREM-1), a cell surface glycoprotein expressed mainly on monocytes, macrophages, and neutrophils, but also on e.g. endothelial cells or bronchial epithelium, plays an important role in innate immune responses. Upon triggering by its ligands (mainly bacterial and fungal components, but also some viruses, such as Marburg or Ebola virus), it initiates signaling cascades leading to release of pro-inflammatory cytokines and chemokines. CD354 is strongly present in infectious inflammatory lesions (e.g. in folliculitis or impetigo), but not so much in non-infectious inflammatory lesions, (e.g. vasculitis or psoriasis). However, under certain conditions neutrophils can upregulate CD354 also under non-infectious inflammatory conditions, e.g. in rheumatoid arthritis. Soluble CD354 (sTREM-1) is an important biomarker for identification of septic patients, as well as for prediction of their survival.,TREM-1
- 基因ID
- 54210
- UniProt
- Q9NP99
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