The mouse monoclonal antibody E3 recognizes an extracellular epitope of CD307a, a transmembrane glycoprotein expressed predominantly on the surface of mature B cells.
纯化方法
Purified by protein-A affinity chromatography.
免疫原
DNA-immunization followed by a boost with the CD307a transfected cells
Fc receptor like 1,CD307a is a type I transmembrane glycoprotein of the Fc receptor family. It contains two ITAM motifs in its cytoplasmic domain. CD307a is expressed mainly on the surface of mature B-cells, and is down-regulated in germinal center B-cells. Expression of CD307a is higher in patients with autoimmune diseases, compared with healthy controls.,FcRL1, FcRH1, IRTA5