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BTLA 抗体

BTLA 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal MIH26 unconjugated
产品编号 ABIN7505891
发货至: 中国
  • 抗原 See all BTLA 抗体
    BTLA (B and T Lymphocyte Associated (BTLA))
    适用
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    人, Non-Human Primate
    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This BTLA antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS)
    原理
    Anti-Hu CD272 Purified
    特异性
    The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
    纯化方法
    Purified by protein-A affinity chromatography.
    免疫原
    cells transfected with human CD272
    克隆位点
    MIH26
    亚型
    IgG2a kappa
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    Discover our top product BTLA Primary Antibody
  • 应用备注
    Flow cytometry: Recommended dilution: 2-5 μg/mL.
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C. Do not freeze.
  • 抗原
    BTLA (B and T Lymphocyte Associated (BTLA))
    别名
    CD272 (BTLA 产品)
    别名
    BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
    背景
    B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
    基因ID
    151888
    UniProt
    Q7Z6A9
    途径
    Cancer Immune Checkpoints
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