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ADAM10 抗体 (PE)

This anti-ADAM10 antibody is a 小鼠 单克隆 antibody detecting ADAM10 in FACS. Suitable for 人.
产品编号 ABIN7505862
发货至: 中国

Quick Overview for ADAM10 抗体 (PE) (ABIN7505862)

抗原

See all ADAM10 抗体
ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ADAM10 antibody is conjugated to PE

应用范围

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Flow Cytometry (FACS)

克隆位点

11G2
  • 原理

    Anti-Hu CD156c PE

    特异性

    The mouse monoclonal antibody 11G2 recognizes an extracellular/luminal epitope of CD156c, a type I transmembrane glycoprotein, serving as a zinc-dependent metalloprotease.

    无交叉反应

    小鼠

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Jurkat cells

    亚型

    IgG1 kappa
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

    别名

    CD156c

    背景

    ADAM metallopeptidase domain 10,CD156c is a type I transmembrane glycoprotein with a zinc-dependent metalloprotease activity. It serves as an endopeptidase of broad specificity, which is expressed mainly in thymus, liver, and muscles. Its expression can be induced in inflamed central nervous system, and in arthritic tissues. CD156c is involved in multiple sclerosis-associated myelin degradation. It also solubilizes various membrane proteins, including CD23, CD44, CD126, CD171, ephrin-A2, and other.,ADAM10, AD10, RAK, MADM, HsT18717

    基因ID

    102

    UniProt

    O14672

    途径

    Notch Signaling, EGFR Signaling Pathway
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