RENT2/UPF2 抗体 (C-Term)
-
- 抗原 See all RENT2/UPF2 (UPF2) 抗体
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This RENT2/UPF2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Rent2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product UPF2 Primary Antibody
-
-
- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
-
Positive Control: Mouse brain Validation: Orthogonal
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- 抗原
- RENT2/UPF2 (UPF2) (UPF2 Regulator of Nonsense Transcripts 2 (UPF2))
- 别名
- Rent2 (UPF2 产品)
- 别名
- HUPF2 antibody, RENT2 antibody, smg-3 antibody, UPF2, regulator of nonsense mediated mRNA decay antibody, UPF2 regulator of nonsense transcripts homolog (yeast) antibody, UPF2 antibody, Upf2 antibody, upf2 antibody
- 背景
-
Synonyms: UPF2 regulator of nonsense mediated mRNA decay , HUPF2 , RENT2 , smg-3
Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene, both variants encode the same protein. [provided by RefSeq]
- 分子量
- 148 kDa
- 基因ID
- 26019
- UniProt
- Q9HAU5
-