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MAFK 抗体

MAFK 适用: 人 WB, ChIP, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7469481
发货至: 中国
  • 抗原 See all MAFK 抗体
    MAFK (Transcription Factor MafK (MAFK))
    适用
    • 29
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    宿主
    • 26
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    克隆类型
    • 26
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    多克隆
    标记
    • 14
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    This MAFK antibody is un-conjugated
    应用范围
    • 23
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    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP)
    交叉反应
    人, 小鼠
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Full length human MAFK Recombinant protein.
    亚型
    IgG
    Top Product
    Discover our top product MAFK Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Jurkat

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    MAFK (Transcription Factor MafK (MAFK))
    别名
    MAFK (MAFK 产品)
    别名
    NFE2U antibody, P18 antibody, AW061068 antibody, NF-E2 antibody, Nfe2u antibody, MAF bZIP transcription factor K antibody, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) antibody, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K antibody, Mafk antibody, MAFK antibody, mafk antibody
    背景

    Synonyms: MAF bZIP transcription factor K , NFE2U , P18

    Background: The developmentally regulated expression of the globin genes depends on upstream regulatory elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen deaminase (PBGD, MIM 609806) and ferrochelatase (FECH, MIM 612386). NFE2 DNA-binding activity consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2 sites.[supplied by OMIM]

    分子量
    18 kDa
    基因ID
    7975
    UniProt
    O60675
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