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GATSL3 抗体

GATSL3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7469300
发货至: 中国
  • 抗原 See all GATSL3 products
    GATSL3 (GATS Protein-Like 3 (GATSL3))
    适用
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 2
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This GATSL3 antibody is un-conjugated
    应用范围
    Western Blotting (WB)
    交叉反应
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GATSL3. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: MCF-7 , MDA-MB-231

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.9 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    GATSL3 (GATS Protein-Like 3 (GATSL3))
    别名
    GATSL3 (GATSL3 产品)
    别名
    2410008K03Rik antibody, RGD1304774 antibody, cytosolic arginine sensor for mTORC1 subunit 1 antibody, GATS protein-like 3 antibody, CASTOR1 antibody, Gatsl3 antibody, Castor1 antibody
    背景

    Synonyms: cytosolic arginine sensor for mTORC1 subunit 1 , GATSL3

    Background: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

    分子量
    36 kDa
    基因ID
    652968
    UniProt
    Q8WTX7
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