GATSL3 抗体
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- 抗原 See all GATSL3 products
- GATSL3 (GATS Protein-Like 3 (GATSL3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GATSL3 antibody is un-conjugated
- 应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human GATSL3. The exact sequence is proprietary.
- 亚型
- IgG
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anti-GATS Protein-Like 3 (GATSL3) (C-Term) antibody
GATSL3 适用: 人, Cow, 犬, 豚鼠, 马, 小鼠, 兔, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: MCF-7 , MDA-MB-231
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.9 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- GATSL3 (GATS Protein-Like 3 (GATSL3))
- 别名
- GATSL3 (GATSL3 产品)
- 别名
- 2410008K03Rik antibody, RGD1304774 antibody, cytosolic arginine sensor for mTORC1 subunit 1 antibody, GATS protein-like 3 antibody, CASTOR1 antibody, Gatsl3 antibody, Castor1 antibody
- 背景
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Synonyms: cytosolic arginine sensor for mTORC1 subunit 1 , GATSL3
Background: Functions as an intracellular arginine sensor within the amino acid-sensing branch of the TORC1 signaling pathway. As a homodimer or a heterodimer with CASTOR2, binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Binding of arginine to CASTOR1 allosterically disrupts the interaction of CASTOR1-containing dimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
- 分子量
- 36 kDa
- 基因ID
- 652968
- UniProt
- Q8WTX7
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